Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Identification of nestin as a urinary biomarker for acute kidney injury. 24503548

2014
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Inhibition of CYP2E1 coupled with the prior induction of Nrf2 may be a valuable tool to reduce CYP2E1-mediated rhabdomyolysis-induced acute kidney injury. 24717297

2014
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD The restoration of kidney mitochondria function by inhibition of angiotensin-II production in rats with acute adriamycin-induced nephrotoxicity. 24502693

2014
Entrez Id: 10763
Gene Symbol: NES
NES
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Identification of nestin as a urinary biomarker for acute kidney injury. 24503548

2014
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation. 24412858

2014
Entrez Id: 3280
Gene Symbol: HES1
HES1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Determination of relative Notch1 and gamma-secretase-related gene expression in puromycin-treated microdissected rat kidneys. 24397211

2013
Entrez Id: 2806
Gene Symbol: GOT2
GOT2
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Cisplatin binding and inactivation of mitochondrial glutamate oxaloacetate transaminase in cisplatin-induced rat nephrotoxicity. 23924727

2013
Entrez Id: 3280
Gene Symbol: HES1
HES1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD [Effect of fermented cordyceps powder and prednisone on the Notch2/Hes-1 signaling activation in the kidney tubules of rats with acute aristolochic acid nephropathy]. 24325066

2013
Entrez Id: 10544
Gene Symbol: PROCR
PROCR
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Heme oxygenase 1 modulates thrombomodulin and endothelial protein C receptor levels to attenuate septic kidney injury. 23807243

2013
Entrez Id: 823
Gene Symbol: CAPN1
CAPN1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options. 24158126

2013
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury. 22414646

2012
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats. 22551254

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Inhibition of poly(ADP-ribose) polymerase attenuates acute kidney injury in sodium taurocholate-induced acute pancreatitis in rats. 22750969

2012
Entrez Id: 7498
Gene Symbol: XDH
XDH
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Nephroprotective efficacy of chrysin against cisplatin-induced toxicity via attenuation of oxidative stress. 22571266

2012
Entrez Id: 4714
Gene Symbol: NDUFB8
NDUFB8
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Persistent disruption of mitochondrial homeostasis after acute kidney injury. 22160772

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Erythropoietin attenuates cardiopulmonary bypass-induced renal inflammatory injury by inhibiting nuclear factor-κB p65 expression. 22659586

2012
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury. 23022334

2012
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Altered regulation of nitric oxide and natriuretic peptide system in cisplatin-induced nephropathy. 22209992

2012
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Annexin A1 protein attenuates cyclosporine-induced renal hemodynamics changes and macrophage infiltration in rats. 22101490

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Erythropoietin attenuates cardiopulmonary bypass-induced renal inflammatory injury by inhibiting nuclear factor-κB p65 expression. 22659586

2012
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury. 22414646

2012
Entrez Id: 10014
Gene Symbol: HDAC5
HDAC5
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney. 21416250

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Celecoxib, a selective cyclooxygenase-2 inhibitor, attenuates renal injury in a rat model of Cisplatin-induced nephrotoxicity. 21893983

2011
Entrez Id: 8841
Gene Symbol: HDAC3
HDAC3
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney. 21416250

2011
Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins. 20037173

2010