|
rs731236
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
The rs731236 variant was shown to be associated with high cholesterol and LDL-cholester</span>ol levels in T2DM patients, while rs1544410 was associated with lower BMI and lower LDL cholesterol levels.
|
28323045 |
2018 |
|
rs731236
|
|
Restless Legs Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Despite results of several recent case-control association studies which have suggested a possible contribution of heme-oxygenase 1 (HMOX1) rs2071746 and vitamin D3 receptor (VDR) rs731236 variants, or the presence of allele 2 of the complex microsatellite repeat Rep1 within the alpha-synuclein (SNCA) gene promoter in modifying the risk for RLS, these studies need to be replicated in further studies involving different populations.
|
29033051 |
2018 |
|
rs731236
|
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
Results Our findings suggest a significant association between rs731236 and prostate cancer risk in Asians and African Americans, but rs1544410 was not associated with prostate cancer under three genetic models.
|
28222630 |
2017 |
|
rs731236
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Epidemiological evidence on the relationships between the vitamin D receptor (VDR) single nucleotide polymorphisms (SNPs) rs731236 (TaqI), rs7975232 (ApaI), rs1544410 (BsmI), and rs2228570 (FokI) and Parkinson's disease (PD) is inconsistent.
|
28216333 |
2017 |
|
rs731236
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The first aim of our study was to examine the association between common variants in VDR [rs2228570 (FokI), rs1544410 (BsmI), rs7975232 (ApaI), rs731236 (TaqI) and rs11568820 (Cdx2)] and lung cancer risk in the Polish population.
|
28411367 |
2017 |
|
rs731236
|
|
Prostate carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Results Our findings suggest a significant association between rs731236 and prostate cancer risk in Asians and African Americans, but rs1544410 was not associated with prostate cancer under three genetic models.
|
28222630 |
2017 |
|
rs731236
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The first aim of our study was to examine the association between common variants in VDR [rs2228570 (FokI), rs1544410 (BsmI), rs7975232 (ApaI), rs731236 (TaqI) and rs11568820 (Cdx2)] and lung cancer risk in the Polish population.
|
28411367 |
2017 |
|
rs731236
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The first aim of our study was to examine the association between common variants in VDR [rs2228570 (FokI), rs1544410 (BsmI), rs7975232 (ApaI), rs731236 (TaqI) and rs11568820 (Cdx2)] and lung cancer risk in the Polish population.
|
28411367 |
2017 |
|
rs731236
|
|
Gestational Diabetes
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our study was aimed to evaluate a possible association between the VDR ApaI (rs7975232) and TaqI (rs731236) gene polymorphisms and susceptibility to GDM in an Iranian pregnant women population.
|
26784653 |
2016 |
|
rs731236
|
|
Nephrolithiasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
To analyze the relationship between nephrolithiasis and vitamin D receptor (VDR) gene BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), Tru9I (rs757343) and FokI (rs2228570) polymorphisms in a study group from the Turkish population.
|
26945655 |
2016 |
|
rs731236
|
|
Kidney Calculi
|
|
0.030 |
GeneticVariation
|
BEFREE |
To analyze the relationship between nephrolithiasis and vitamin D receptor (VDR) gene BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), Tru9I (rs757343) and FokI (rs2228570) polymorphisms in a study group from the Turkish population.
|
26945655 |
2016 |
|
rs731236
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Among the results, eight VDR SNPs, namely rs2254210, rs1540339, rs2107301, rs11168267, rs11574113, rs731236, rs3847987 and rs11574143, the latter 5 of which were located in the 3' region, were nominally associated with the risk of colorectal cancer (P = 0.01-0.048).
|
27736940 |
2016 |
|
rs731236
|
|
Prostate carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
rs731236 and rs7975232 were significantly associated with PCa risk (p<0.05).
|
25750310 |
2015 |
|
rs731236
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Homozygotes for the rs731236 TT (major allele) genotype had a 31% lower risk of PD risk (OR=0.69; 95% CI=0.49, 0.98; p=0.04 for TT vs. TC+CC).
|
25890641 |
2015 |
|
rs731236
|
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
rs731236 and rs7975232 were significantly associated with PCa risk (p<0.05).
|
25750310 |
2015 |
|
rs731236
|
|
Restless Legs Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
None of the SNPs studied was related with the positivity of family history of RLS.These results suggest a modest, but significant association between VDR rs731236 SNP and the risk for RLS.
|
26632733 |
2015 |
|
rs731236
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The genotype and haplotype frequencies of four VDR polymorphisms, FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232) and TaqI (rs731236) were studied using polymerase chain reaction and restriction fragment length polymorphism analysis in 240 patients with lung cancer and 280 healthy controls.
|
24996287 |
2014 |
|
rs731236
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The genotype and haplotype frequencies of four VDR polymorphisms, FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232) and TaqI (rs731236) were studied using polymerase chain reaction and restriction fragment length polymorphism analysis in 240 patients with lung cancer and 280 healthy controls.
|
24996287 |
2014 |
|
rs731236
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The genotype and haplotype frequencies of four VDR polymorphisms, FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232) and TaqI (rs731236) were studied using polymerase chain reaction and restriction fragment length polymorphism analysis in 240 patients with lung cancer and 280 healthy controls.
|
24996287 |
2014 |
|
rs731236
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Unadjusted and adjusted hazard ratios for all-cause mortality (469 events) and CRC-specific mortality (336 events) were estimated for VDR variants rs731236 (TaqI), rs2228570 (FokI), rs11568820 (Cdx2), and rs1989969 (VDR-5132).
|
24075799 |
2013 |
|
rs731236
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
There were no significant differences in the genotype and allele frequencies of VDR rs4334089 and rs731236 polymorphisms between the group of patients with PD and the control group in a Chinese Han population (for VDR rs4334089: OR 1.02, 95% CI: 0.85-1.23; for VDR rs731236: OR 1.13, 95% CI: 0.75-1.71).
|
22947263 |
2013 |
|
rs731236
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
Results showed T2DM to be significantly associated with the VDR Taq1 (rs731236-AG) and Bsm-I (rs1544410-CT) genotypes, and the VDR rs1544410-T allele.
|
22219324 |
2012 |
|
rs731236
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
A total of 9, 5, 3, and 7 studies were finally included in the analyses for the associations between the VDR TaqI (rs731236), FokI (rs2228570), ApaI (rs7975232), or aggrecan VNTR polymorphisms and the risk of IDD, respectively.
|
23209686 |
2012 |
|
rs731236
|
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
We also examined vitamin D related genes, VDR and CYP27B1, and found a significant association of PCa with the TaqI polymorphism (rs731236) in the former.
|
21358824 |
2011 |
|
rs731236
|
|
Prostate carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We also examined vitamin D related genes, VDR and CYP27B1, and found a significant association of PCa with the TaqI polymorphism (rs731236) in the former.
|
21358824 |
2011 |