Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.400 None 0.914 35 1 1991 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.100 None 0.971 35 0 1983 2018
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.100 None 0.971 34 0 1992 2019
Entrez Id: 27436
Gene Symbol: EML4
EML4
Q9HC35 EMAP like 4 100 0.569 0.577 4.8E-04 0.100 None 1.000 33 0 2008 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 0.970 33 0 1998 2014
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.400 None 1.000 33 0 1990 2019
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.100 None 1.000 33 0 2012 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.100 None 0.968 31 0 1998 2014
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.400 None 0.966 29 0 1986 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 1.000 29 0 1988 2018
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.400 None 0.962 26 0 2001 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.400 None 0.962 26 0 1998 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.100 None 1.000 25 0 1993 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 0.917 24 0 2001 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.100 None 0.917 24 0 1992 2017
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 225 0.486 0.808 9.4E-10 0.400 None 1.000 23 0 1994 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 559 0.388 0.846 9.1E-11 0.400 None 0.870 23 0 1993 2020
Entrez Id: 10970
Gene Symbol: CKAP4
CKAP4
Q07065 cytoskeleton associated protein 4 332 0.436 0.731 0.51 0.100 None 0.952 21 0 2001 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.100 None 1.000 21 0 1994 2015
Entrez Id: 4585
Gene Symbol: MUC4
MUC4
Q99102 mucin 4, cell surface associated 183 0.506 0.769 2.8E-54 0.100 None 1.000 21 0 1996 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.100 None 0.900 20 1 2001 2019
Entrez Id: 6121
Gene Symbol: RPE65
RPE65
Q16518 retinoid isomerohydrolase RPE65 Enzyme 431 0.417 0.808 6.5E-14 0.100 None 0.950 20 0 2001 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 20 0 2002 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.100 None 1.000 20 8 2000 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 1.000 20 1 1991 2017