Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.700 None 1.000 12 0 1998 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 12 0 2003 2019
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.390 None 1.000 11 0 2004 2009
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.390 None 1.000 11 0 1994 2019
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.100 None 1.000 11 0 2003 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.380 None 1.000 11 0 2000 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.390 None 1.000 11 0 2003 2018
Entrez Id: 9052
Gene Symbol: GPRC5A
GPRC5A
Q8NFJ5 G protein-coupled receptor class C group 5 member A G-protein coupled receptor 90 0.579 0.692 6.8E-08 0.100 None 1.000 11 0 2007 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.390 None 1.000 10 0 2002 2008
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 1.000 10 0 1992 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.380 None 1.000 10 0 1997 2008
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.100 None 1.000 10 0 2004 2015
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 1.000 10 0 1994 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.090 None 1.000 9 0 1987 2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.580 None 1.000 9 0 2003 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.380 None 1.000 9 0 2002 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.090 None 1.000 9 0 2001 2018
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
Q14145 kelch like ECH associated protein 1 251 0.475 0.808 3.9E-04 0.090 None 0.889 9 0 2006 2019
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
P11509 cytochrome P450 family 2 subfamily A member 6 133 0.556 0.731 5.4E-09 0.340 None 1.000 8 0 1999 2015
Entrez Id: 1789
Gene Symbol: DNMT3B
DNMT3B
Q9UBC3 DNA methyltransferase 3 beta 315 0.453 0.846 0.20 0.080 None 1.000 8 0 2002 2015
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Q08050 forkhead box M1 323 0.441 0.769 7.4E-04 0.370 None 1.000 8 0 2006 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.080 None 1.000 8 0 2011 2019
Entrez Id: 27436
Gene Symbol: EML4
EML4
Q9HC35 EMAP like 4 100 0.569 0.577 4.8E-04 0.080 None 1.000 8 0 2008 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.080 None 1.000 8 0 2005 2017
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.370 None 1.000 8 0 1998 2016