Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.100 None 1.000 33 0 2010 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.100 None 1.000 29 0 2001 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 0.962 26 0 2008 2019
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.100 None 1.000 18 0 1993 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 17 0 2013 2019
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2
P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 317 0.456 0.846 3.5E-08 0.100 None 1.000 15 0 2003 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 325 0.453 0.846 0.14 0.100 None 1.000 15 0 2003 2019
Entrez Id: 5564
Gene Symbol: PRKAB1
PRKAB1
Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 296 0.460 0.846 5.3E-03 0.100 None 1.000 15 0 2003 2019
Entrez Id: 7350
Gene Symbol: UCP1
UCP1
P25874 uncoupling protein 1 Transporter 124 0.545 0.769 1.7E-11 0.100 None 1.000 13 0 1999 2019
Entrez Id: 151306
Gene Symbol: GPBAR1
GPBAR1
Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 122 0.548 0.731 1.4E-09 0.100 None 1.000 13 0 2011 2019
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
O15516 clock circadian regulator 309 0.463 0.885 1.00 0.100 None 1.000 12 0 2007 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.400 None 0.909 11 0 2006 2020
Entrez Id: 56729
Gene Symbol: RETN
RETN
Q9HD89 resistin 302 0.454 0.808 3.7E-02 0.100 None 1.000 11 0 2007 2020
Entrez Id: 2167
Gene Symbol: FABP4
FABP4
P15090 fatty acid binding protein 4 194 0.500 0.808 5.2E-05 0.100 None 1.000 11 0 2016 2020
Entrez Id: 5053
Gene Symbol: PAH
PAH
P00439 phenylalanine hydroxylase 219 0.516 0.769 6.4E-23 0.100 None 1.000 11 0 1991 2019
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.100 None 0.909 11 0 2007 2018
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 1.000 10 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 10 0 2002 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.090 None 1.000 9 0 2006 2019
Entrez Id: 948
Gene Symbol: CD36
CD36
P16671 CD36 molecule Receptor 351 0.446 0.846 1.1E-60 0.090 None 1.000 9 0 2002 2020
Entrez Id: 55908
Gene Symbol: ANGPTL8
ANGPTL8
Q6UXH0 angiopoietin like 8 54 0.650 0.577 6.9E-12 0.090 None 1.000 9 0 2017 2019
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.080 None 1.000 8 0 2017 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.080 None 1.000 8 0 1998 2017
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
P28845 hydroxysteroid 11-beta dehydrogenase 1 163 0.520 0.731 0.42 0.080 None 1.000 8 0 2010 2019
Entrez Id: 6319
Gene Symbol: SCD
SCD
O00767 stearoyl-CoA desaturase 225 0.490 0.808 0.97 0.080 None 1.000 8 0 2004 2019