Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 P01912 P04229 P13760 P13761 P20039 Q29974 Q30134 Q30167 Q5Y7A7 Q95IE3 Q9GIY3 Q9TQE0 major histocompatibility complex, class II, DR beta 1 defense/immunity protein 719 0.347 0.897 1.0E-03 0.060 1.000 6 0 1995 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.040 1.000 4 0 2007 2010
Entrez Id: 6737
Gene Symbol: TRIM21
TRIM21
P19474 tripartite motif containing 21 109 0.536 0.690 2.9E-09 0.040 0.750 4 0 1987 2009
Entrez Id: 831
Gene Symbol: CAST
CAST
P20810 calpastatin 92 0.565 0.724 3.9E-12 0.030 1.000 3 0 1995 2003
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV, pyrin innate immunity regulator 199 0.494 0.724 1.0E-14 0.030 1.000 3 0 2004 2015
Entrez Id: 6738
Gene Symbol: TROVE2
TROVE2
P10155 TROVE domain family member 2 nucleic acid binding 32 0.652 0.517 0.54 0.020 1.000 2 0 2004 2006
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 470 0.399 0.862 3.7E-03 0.020 2 0 2005 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.020 1.000 2 0 2008 2008
Entrez Id: 8741
Gene Symbol: TNFSF13
TNFSF13
O75888 TNF superfamily member 13 90 0.561 0.655 0.79 0.020 0.500 2 0 2002 2012
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
Q9NZ08 endoplasmic reticulum aminopeptidase 1 hydrolase; protease 69 0.627 0.517 3.1E-26 0.020 1.000 2 0 2016 2016
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
O14786 neuropilin 1 136 0.521 0.690 1.00 0.010 < 0.001 1 0 2013 2013
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.010 1.000 1 0 2001 2001
Entrez Id: 7429
Gene Symbol: VIL1
VIL1
P09327 villin 1 cytoskeletal protein 18 0.720 0.310 1.8E-14 0.010 1.000 1 0 1996 1996
Entrez Id: 7432
Gene Symbol: VIP
VIP
P01282 vasoactive intestinal peptide signaling molecule 152 0.526 0.759 3.9E-04 0.010 1.000 1 0 2011 2011
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 184 0.486 0.862 7.2E-03 0.010 1.000 1 0 2014 2014
Entrez Id: 8163
Gene Symbol: CDR3
CDR3
Cerebellar degeneration-related autoantigen-3 148 0.499 0.724 0.010 1.000 1 0 1994 1994
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
Q13077 TNF receptor associated factor 1 signaling molecule 76 0.580 0.690 1.2E-02 0.010 1.000 1 0 2010 2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.010 1.000 1 0 2000 2000
Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
P78423 C-X3-C motif chemokine ligand 1 signaling molecule 123 0.533 0.759 0.88 0.010 1 0 2006 2006
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
Q8N474 secreted frizzled related protein 1 enzyme modulator; receptor; signaling molecule 156 0.500 0.759 0.97 0.010 1.000 1 0 1998 1998
Entrez Id: 6708
Gene Symbol: SPTA1
SPTA1
P02549 spectrin alpha, erythrocytic 1 37 0.696 0.310 2.9E-18 0.010 1.000 1 0 2016 2016
Entrez Id: 6711
Gene Symbol: SPTBN1
SPTBN1
Q01082 spectrin beta, non-erythrocytic 1 36 0.667 0.483 1.00 0.010 1.000 1 0 2001 2001
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 nucleic acid binding; transcription factor 292 0.464 0.759 0.36 0.010 1 0 2008 2008
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
T cell receptor beta variable 20/OR9-2 (non-functional) 319 0.423 0.897 0.010 < 0.001 1 0 2002 2002
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 nucleic acid binding; transcription factor 161 0.518 0.690 8.5E-03 0.010 1.000 1 0 2012 2012