Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.700 None 0.960 99 35 1990 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 0.985 68 7 1990 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.200 None 1.000 19 5 2002 2018
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.720 None 1.000 6 4 2012 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 16 3 2002 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.050 None 1.000 5 3 2006 2019
Entrez Id: 567
Gene Symbol: B2M
B2M
P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.100 None 1.000 1 3 2016 2016
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.400 None 0.857 28 2 1991 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.905 21 2 1989 2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.500 None 0.923 13 2 1998 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.040 None 0.750 4 2 2002 2015
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
HOX transcript antisense RNA 234 0.475 0.769 0.040 None 1.000 4 2 2014 2018
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.020 None 1.000 2 2 1989 2004
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like Enzyme 110 0.551 0.654 4.4E-05 0.010 None < 0.001 1 2 2013 2013
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 110 0.593 0.577 2.1E-06 0.100 None 1.000 1 2 2017 2017
Entrez Id: 84700
Gene Symbol: MYO18B
MYO18B
Q8IUG5 myosin XVIIIB 63 0.628 0.615 1.0E-31 0.310 None 1.000 1 2 2002 2002
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 0.977 44 1 1994 2020
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.090 None 1.000 9 1 2002 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.080 None 1.000 8 1 2014 2018
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.050 None 1.000 5 1 1997 2010
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.050 None 1.000 5 1 1995 2019
Entrez Id: 1644
Gene Symbol: DDC
DDC
P20711 dopa decarboxylase 164 0.535 0.769 3.8E-08 0.050 None 1.000 5 1 1987 2020
Entrez Id: 65975
Gene Symbol: STK33
STK33
Q9BYT3 serine/threonine kinase 33 Kinase 43 0.666 0.346 2.2E-06 0.120 None 1.000 3 1 2017 2019
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
Q92887 ATP binding cassette subfamily C member 2 Transporter 254 0.483 0.808 5.2E-47 0.020 None 1.000 2 1 1999 2012
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
Q03405 plasminogen activator, urokinase receptor 147 0.536 0.731 5.3E-03 0.020 None 1.000 2 1 2009 2013