Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.100 None 1.000 13 3 2004 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.100 None 1.000 12 2 1996 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.100 None 1.000 12 1 1998 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 1999 2019
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
microRNA 203a 237 0.471 0.808 0.100 None 1.000 12 0 2013 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.100 None 1.000 12 2 1997 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 12 0 2008 2019
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
P58062 serine peptidase inhibitor Kazal type 7 25 0.722 0.308 7.8E-02 0.100 None 1.000 12 0 2003 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 1.000 11 0 2009 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.100 None 1.000 11 0 1991 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 11 0 2005 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 11 0 1998 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.818 11 1 2005 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.100 None 1.000 10 0 2007 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.100 None 1.000 10 1 1991 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.100 None 0.900 10 2 1997 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 1.000 10 0 2003 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.100 None 0.900 10 0 2012 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.090 None 1.000 9 0 1998 2018
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.090 None 1.000 9 2 2003 2019
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.090 None 1.000 9 0 2012 2019
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.090 None 1.000 9 0 1997 2006
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
microRNA 145 366 0.431 0.846 0.090 None 1.000 9 0 2012 2020
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.090 None 1.000 9 0 2010 2019
Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
P48029 solute carrier family 6 member 8 Transporter 274 0.476 0.846 1.00 0.090 None 0.889 9 0 2012 2019