Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.400 None 1.000 32 0 1995 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 30 0 2002 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 1.000 22 0 1996 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.400 None 1.000 21 0 2007 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 1.000 19 0 2015 2019
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.400 None 1.000 18 0 2011 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 1.000 16 0 1999 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 14 0 2012 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 1.000 13 0 2009 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.100 None 1.000 12 0 2012 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.100 None 1.000 12 0 2015 2019
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.100 None 1.000 11 0 2010 2019
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
P35247 surfactant protein D Surfactant 194 0.500 0.846 7.5E-05 0.100 None 1.000 11 0 2008 2019
Entrez Id: 3567
Gene Symbol: IL5
IL5
P05113 interleukin 5 359 0.437 0.846 5.7E-03 0.090 None 1.000 9 0 2001 2019
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.090 None 1.000 9 0 2008 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.090 None 1.000 9 0 2017 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.080 None 1.000 8 0 2008 2019
Entrez Id: 26073
Gene Symbol: POLDIP2
POLDIP2
Q9Y2S7 DNA polymerase delta interacting protein 2 530 0.396 0.923 0.41 0.080 None 1.000 8 0 2008 2019
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1
O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.080 None 1.000 8 0 2008 2019
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A
Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 523 0.397 0.923 2.5E-02 0.080 None 1.000 8 0 2008 2019
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 555 0.393 0.923 8.0E-03 0.080 None 1.000 8 0 2008 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.370 None 1.000 8 0 2013 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.080 None 1.000 8 0 2010 2020
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2
O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.080 None 1.000 8 0 2008 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.080 None 1.000 8 0 2014 2019