Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.550 GeneticVariation group BEFREE These data suggest that p53 mutation may be a very early event in oral cavity tumor progression and demonstrate that pre-malignant lesions obtained from non-tobacco users do not exhibit p53 mutations. 7829258 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.550 GeneticVariation group LHGDN Association between the TP53 codon72 polymorphism and oral cancer risk and prognosis. 17306604 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.550 GeneticVariation group LHGDN Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers. 18701437 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.550 GeneticVariation group LHGDN Association of p53 and p21(CDKN1A/WAF1/CIP1) polymorphisms with oral cancer in Taiwan patients. 17595776 2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.310 GeneticVariation group BEFREE Although it is unclear why different codon 12 alleles occur in different disease contexts and the complex interactions between tumor genotype and phenotype need clarification, on the basis of our results the presence of KRAS p.G12V/R favors the adenomatoid odontogenic tumor diagnosis in challenging oral neoplasm cases. 30643167 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.210 GeneticVariation group BEFREE Oral tumor specimens (n = 50) from eastern Indian population were studied for the presence of mutations in the H-, K- and N-ras genes using selective oligodeoxynucleotide hybridization and restriction fragment length polymorphism analysis of polymerase chain reaction-amplified products. 10889924 2000
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.030 GeneticVariation group LHGDN Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer. 18838881 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.030 GeneticVariation group LHGDN A metalloproteinase-9 polymorphism which affects its expression is associated with increased risk for oral squamous cell carcinoma. 17498910 2008
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.030 GeneticVariation group LHGDN Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population. 12016153 2002
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.030 GeneticVariation group LHGDN CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses. 19160101 2009
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.020 GeneticVariation group LHGDN The interleukin-10 (-1082A/G) polymorphism is strongly associated with increased risk for oral squamous cell carcinoma. 18383862 2008
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
0.020 GeneticVariation group LHGDN Association of XRCC4 codon 247 polymorphism with oral cancer susceptibility in Taiwan. 18630527 2008
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
0.020 GeneticVariation group LHGDN A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer. 18225566 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.020 GeneticVariation group LHGDN CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma. 18061526 2008
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
0.020 GeneticVariation group LHGDN Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan. 18410587 2008
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.010 GeneticVariation group LHGDN Urokinase gene 3'-UTR T/C polymorphism is associated with oral cancer. 15356878 2004
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.010 GeneticVariation group LHGDN Increased risk of oral cancer in relation to common Indian mitochondrial polymorphisms and Autosomal GSTP1 locus. 17886251 2007
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.010 GeneticVariation group LHGDN Association of p53 and p21(CDKN1A/WAF1/CIP1) polymorphisms with oral cancer in Taiwan patients. 17595776 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.010 GeneticVariation group LHGDN The interleukin-1 beta gene polymorphism +3953 C/T is not associated with risk for oral cancer. 18225559 2008
Entrez Id: 7161
Gene Symbol: TP73
TP73
0.010 GeneticVariation group LHGDN Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers. 18701437 2008
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
0.010 GeneticVariation group LHGDN A novel single nucleotide polymorphism in ERCC6 gene is associated with oral cancer susceptibility in Taiwanese patients. 17933579 2008
Entrez Id: 3673
Gene Symbol: ITGA2
ITGA2
0.010 GeneticVariation group LHGDN Association of platelet glycoprotein Ia polymorphism with minor increase of risk for oral cancer. 16513317 2006
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
0.010 GeneticVariation group LHGDN Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan. 18410587 2008
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2
0.010 GeneticVariation group LHGDN Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan. 18410587 2008
Entrez Id: 1361
Gene Symbol: CPB2
CPB2
0.010 GeneticVariation group LHGDN The 1040C/T polymorphism influencing thermal stability and activity of thrombin activatable fibrinolysis inhibitor is associated with risk for oral cancer. 17636471 2007