Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
0.300 Biomarker group CTD_human Multiple ADH genes are associated with upper aerodigestive cancers. 18500343 2008
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
0.300 Biomarker group CTD_human Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde. 15138216 2004
Entrez Id: 131
Gene Symbol: ADH7
ADH7
0.300 Biomarker group CTD_human Multiple ADH genes are associated with upper aerodigestive cancers. 18500343 2008
Entrez Id: 10551
Gene Symbol: AGR2
AGR2
0.010 AlteredExpression group BEFREE In addition, Anterior gradient 2 (agr2), a pro-oncogenic signaling intermediate, was identified from gene expression profiling, and overexpression of AGR2 showed a positive correlation with oral tumor metastasis. 23834814 2013
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
0.300 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
0.300 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
0.300 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
0.300 Biomarker group CTD_human Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin. 12509969 2003
Entrez Id: 648
Gene Symbol: BMI1
BMI1
0.010 Biomarker group LHGDN Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival. 17179983 2007
Entrez Id: 682
Gene Symbol: BSG
BSG
0.010 Biomarker group LHGDN EMMPRIN modulates migration and deposition of TN-C in oral squamous carcinoma. 18751374 2008
Entrez Id: 135398
Gene Symbol: C6orf141
C6orf141
0.010 Biomarker group BEFREE Xenograft tumor growth assay revealed that C6orf141 could significantly suppress oral tumor growth in vivo. 30872783 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.010 AlteredExpression group LHGDN Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines. 14719121 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.300 Biomarker group CTD_human Focal adhesion kinase knockdown in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis via downregulating MCP-1/CCL2 expression. 25199511 2015
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.020 AlteredExpression group LHGDN Abnormal beta-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features. 15791567 2005
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.020 GeneticVariation group LHGDN CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma. 18061526 2008
Entrez Id: 921
Gene Symbol: CD5
CD5
0.010 GeneticVariation group BEFREE Multiplexed PCR revealed homozygous deletion of leu1 in one oral cavity tumor. 10502719 1999
Entrez Id: 991
Gene Symbol: CDC20
CDC20
0.010 AlteredExpression group LHGDN Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer. 16777988 2007
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
0.010 AlteredExpression group LHGDN Early overexpression of Cdk4 and possible role of KRF and c-myc in chewing tobacco mediated oral cancer development. 14672406 2003
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.010 GeneticVariation group LHGDN Association of p53 and p21(CDKN1A/WAF1/CIP1) polymorphisms with oral cancer in Taiwan patients. 17595776 2007
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
0.010 Biomarker group LHGDN Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line. 12684618 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.340 AlteredExpression group LHGDN Immunohistochemical detection of p16INK4a in dysplastic lesions of the oral cavity. 16799478 2006
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.340 PosttranslationalModification group LHGDN Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer. 12684640 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.340 Biomarker group BEFREE The incidence of hypermethylation in oral tumor and adjacent mucosa for p16 gene was 66.7 and 50%, for DAPK was 68.3 and 60%, and MGMT gene was 51.7 and 26.7%, respectively. 14693237 2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.340 AlteredExpression group LHGDN Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer. 14719099 2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.340 Biomarker group CTD_human Promoter region hypermethylation and mRNA expression of MGMT and p16 genes in tissue and blood samples of human premalignant oral lesions and oral squamous cell carcinoma. 24991542 2014