Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.110 Biomarker group HPO
Entrez Id: 7486
Gene Symbol: WRN
WRN 		0.100 Biomarker group HPO
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		0.100 Biomarker group HPO
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.550 GeneticVariation group BEFREE These data suggest that p53 mutation may be a very early event in oral cavity tumor progression and demonstrate that pre-malignant lesions obtained from non-tobacco users do not exhibit p53 mutations. 7829258 1995
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 AlteredExpression group BEFREE Thus, gene therapy of human oral cancer by increasing the expression of MnSOD activity in target cells might be used to prevent or reduce human oral tumor malignancy. 9095410 1997
Entrez Id: 921
Gene Symbol: CD5
CD5 		0.010 GeneticVariation group BEFREE Multiplexed PCR revealed homozygous deletion of leu1 in one oral cavity tumor. 10502719 1999
Entrez Id: 10301
Gene Symbol: DLEU1
DLEU1 		0.010 GeneticVariation group BEFREE Multiplexed PCR revealed homozygous deletion of leu1 in one oral cavity tumor. 10502719 1999
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.210 GeneticVariation group BEFREE Oral tumor specimens (n = 50) from eastern Indian population were studied for the presence of mutations in the H-, K- and N-ras genes using selective oligodeoxynucleotide hybridization and restriction fragment length polymorphism analysis of polymerase chain reaction-amplified products. 10889924 2000
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.030 GeneticVariation group LHGDN Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population. 12016153 2002
Entrez Id: 220064
Gene Symbol: LTO1
LTO1 		0.010 AlteredExpression group LHGDN High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells. 12172009 2002
Entrez Id: 7378
Gene Symbol: UPP1
UPP1 		0.010 AlteredExpression group LHGDN Uridine phosphorylase is a potential prognostic factor in patients with oral squamous cell carcinoma. 12115385 2002
Entrez Id: 1890
Gene Symbol: TYMP
TYMP 		0.010 AlteredExpression group LHGDN Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma. 12429983 2002
Entrez Id: 2947
Gene Symbol: GSTM3
GSTM3 		0.010 GeneticVariation group LHGDN Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population. 12016153 2002
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.010 GeneticVariation group LHGDN Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population. 12016153 2002
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6 		0.010 GeneticVariation group LHGDN CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka. 11960911 2002
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.520 Biomarker group CTD_human Elevated expression of cyclooxygenase (COX)-2 in oral squamous cell carcinoma--evidence for COX-2 induction by areca quid ingredients in oral keratinocytes. 12969226 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.340 PosttranslationalModification group LHGDN Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer. 12684640 2003
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Biomarker group CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic group CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B 		0.300 Biomarker group CTD_human Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin. 12509969 2003
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.110 AlteredExpression group LHGDN Early overexpression of Cdk4 and possible role of KRF and c-myc in chewing tobacco mediated oral cancer development. 14672406 2003
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		0.010 AlteredExpression group LHGDN Early overexpression of Cdk4 and possible role of KRF and c-myc in chewing tobacco mediated oral cancer development. 14672406 2003
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B 		0.010 Biomarker group LHGDN Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line. 12684618 2003
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.010 Biomarker group LHGDN Toll-like receptor signaling in anti-cancer immunity. 12630564 2003
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.010 PosttranslationalModification group LHGDN Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer. 12684640 2003