Gene: MUTYH ×
Source: INFERRED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli. 16134147 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. 20848659 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. 24733792 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. 12606733 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients. 16287072 2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. 19732775 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype. 16557584 2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases. 25892863 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Mutational spectrum of the APC and MUTYH genes and genotype-phenotype correlations in Brazilian FAP, AFAP, and MAP patients. 23561487 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Germline mutations of the MYH gene in Korean patients with multiple colorectal adenomas. 17703316 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis. 20418187 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families. 23729658 2013
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. 19953527 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Simplifying the detection of MUTYH mutations by high resolution melting analysis. 20687945 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer. 24799981 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain. 25820570 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Increased colorectal cancer incidence in obligate carriers of heterozygous mutations in MUTYH. 19394335 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR MUTYH-associated colorectal cancer and adenomatous polyposis. 23605219 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population. 26694661 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. 25559809 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. 20816984 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management. 25931827 2015