Gene: MUTYH ×
Source: INFERRED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MUTYH gene variants and breast cancer in a Dutch case–control study. 22297469 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients. 16287072 2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis. 15188161 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli. 16134147 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. 20848659 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. 24733792 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients. 18301448 2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. 19953527 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer. 21171015 2011
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. 12606733 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair. 11092888 2001
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer. 22641385 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events. 23361220 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients. 16287072 2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations? 19531215 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MUTYH-associated polyposis - variability of the clinical phenotype in patients with biallelic and monoallelic MUTYH mutations and report on novel mutations. 20618354 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Analysis of inherited MYH/(MutYH) mutations in British Asian patients with colorectal cancer. 17369389 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer. 19836313 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations. 16207212 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. 19732775 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MutYH mutation carriers have increased breast cancer risk. 21952991 2012