Gene: MUTYH ×
Source: INFERRED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair. 11092888 2001
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair. 11092888 2001
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations. 12393807 2002
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe. 11805113 2002
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6. 11801590 2002
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. 12606733 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. 12707038 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH. 12853198 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. 14633673 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. 12606733 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. 14633673 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis. 15188161 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. 15366000 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. 15366000 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. 15236166 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Colorectal cancer and inherited mutations in base-excision repair. 15465463 2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli. 16134147 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations. 16207212 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas. 15890374 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli. 16134147 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations. 15761860 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients. 15635083 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. 15673720 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Germline susceptibility to colorectal cancer due to base-excision repair gene defects. 15931596 2005