Gene: MUTYH ×
Source: INFERRED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer. 25938944 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants. 21063410 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. 20816984 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. 20848659 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. 20848659 2010
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer. 19836313 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer. 22641385 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Analysis of inherited MYH/(MutYH) mutations in British Asian patients with colorectal cancer. 17369389 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. 19032956 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas. 19793053 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas. 19793053 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Association of monoallelic MUTYH mutation among Egyptian patients with colorectal cancer. 27631816 2017
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. 19841264 2009
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations. 16207212 2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH. 12853198 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Base excision repair and the role of MUTYH. 19725997 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Base-excision repair of oxidative DNA damage. 17581577 2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations. 12393807 2002
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer. 21171015 2011
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. 22926731 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases. 25892863 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases. 25892863 2015
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 CausalMutation group CLINVAR Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. 14633673 2003
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		0.100 GeneticVariation group CLINVAR Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. 14633673 2003