Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 384
Gene Symbol: ARG2
ARG2
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 6498
Gene Symbol: SKIL
SKIL
0.200 Biomarker phenotype RGD [Effect of tetramethylpyrazine on expression of Smad7 and SnoN in rats with UUO]. 19382458 2009
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
0.200 Biomarker phenotype RGD A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. 20660018 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.200 Biomarker phenotype RGD The effects of dietary fish oil on inflammation, fibrosis and oxidative stress associated with obstructive renal injury in rats. 21370451 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.200 Biomarker phenotype RGD Expression of LFA-1 (CD11a/CD18) and ICAM-1 (CD54) in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction. 10930117 2000
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.200 Biomarker phenotype RGD Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. 19223006 2009
Entrez Id: 554
Gene Symbol: AVPR2
AVPR2
0.200 Biomarker phenotype RGD Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. 18971210 2009
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
0.200 Biomarker phenotype RGD Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy. 24761003 2014
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
0.200 Biomarker phenotype RGD Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction. 17475897 2007
Entrez Id: 207
Gene Symbol: AKT1
AKT1
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.200 Biomarker phenotype RGD Time course of cytokine mRNA expression in kidneys of rats with unilateral ureteral obstruction. 10644908 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.200 Biomarker phenotype RGD Interferon-γ improves renal interstitial fibrosis and decreases intrarenal vascular resistance of hydronephrosis in an animal model. 21216449 2011
Entrez Id: 5062
Gene Symbol: PAK2
PAK2
0.200 Biomarker phenotype RGD Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. 15629889 2005
Entrez Id: 383
Gene Symbol: ARG1
ARG1
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
0.200 Biomarker phenotype RGD Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. 12787392 2003
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.200 Biomarker phenotype RGD [Renoprotective effects of nonselective endothelin receptor antagonist bosentan on rats with interstitial fibrosis following unilateral ureteral obstruction]. 12887768 2003
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
0.200 Biomarker phenotype RGD The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO). 20734248 2011
Entrez Id: 112
Gene Symbol: ADCY6
ADCY6
0.200 Biomarker phenotype RGD Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. 18971210 2009
Entrez Id: 2671
Gene Symbol: GFER
GFER
0.200 Biomarker phenotype RGD Augmenter of liver regeneration ameliorates renal fibrosis in rats with obstructive nephropathy. 24844766 2014
Entrez Id: 2702
Gene Symbol: GJA5
GJA5
0.200 Biomarker phenotype RGD Expression of connexins in the normal and obstructed developing kidney. 12644912 2003
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
0.200 Biomarker phenotype RGD Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney. 18987110 2009
Entrez Id: 1573
Gene Symbol: CYP2J2
CYP2J2
0.200 Biomarker phenotype RGD Macrophage epoxygenase determines a profibrotic transcriptome signature. 25840911 2015