Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 384
Gene Symbol: ARG2
ARG2
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
0.200 Therapeutic phenotype RGD Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. 25707520 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.200 Therapeutic phenotype RGD Effect of lisinopril on renal tissue damage in unilateral ureteral obstruction in rats. 21667191 2012
Entrez Id: 6498
Gene Symbol: SKIL
SKIL
0.200 Biomarker phenotype RGD [Effect of tetramethylpyrazine on expression of Smad7 and SnoN in rats with UUO]. 19382458 2009
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
0.200 Biomarker phenotype RGD A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. 20660018 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.200 Therapeutic phenotype RGD Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. 25707520 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.200 Biomarker phenotype RGD The effects of dietary fish oil on inflammation, fibrosis and oxidative stress associated with obstructive renal injury in rats. 21370451 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.200 Biomarker phenotype RGD Expression of LFA-1 (CD11a/CD18) and ICAM-1 (CD54) in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction. 10930117 2000
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.200 Biomarker phenotype RGD Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. 19223006 2009
Entrez Id: 554
Gene Symbol: AVPR2
AVPR2
0.200 Biomarker phenotype RGD Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. 18971210 2009
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
0.200 Therapeutic phenotype RGD Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression. 28063381 2017
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
0.200 Biomarker phenotype RGD Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy. 24761003 2014
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
0.200 Biomarker phenotype RGD Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction. 17475897 2007
Entrez Id: 207
Gene Symbol: AKT1
AKT1
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.200 Biomarker phenotype RGD Time course of cytokine mRNA expression in kidneys of rats with unilateral ureteral obstruction. 10644908 2000
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.200 Therapeutic phenotype RGD Upregulated expression of transforming growth factor-beta, type IV collagen, and plasminogen activator inhibitor-1 mRNA are decreased after release of unilateral ureteral obstruction. 12365557 2002
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.200 Biomarker phenotype RGD Interferon-γ improves renal interstitial fibrosis and decreases intrarenal vascular resistance of hydronephrosis in an animal model. 21216449 2011
Entrez Id: 5062
Gene Symbol: PAK2
PAK2
0.200 Biomarker phenotype RGD Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. 15629889 2005
Entrez Id: 383
Gene Symbol: ARG1
ARG1
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 842
Gene Symbol: CASP9
CASP9
0.200 Therapeutic phenotype RGD Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides. 29781318 2018
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
0.200 Biomarker phenotype RGD Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. 12787392 2003
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.200 Biomarker phenotype RGD [Renoprotective effects of nonselective endothelin receptor antagonist bosentan on rats with interstitial fibrosis following unilateral ureteral obstruction]. 12887768 2003