Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5971
Gene Symbol: RELB
RELB
0.200 Biomarker phenotype RGD Rapid communication. Enalapril decreases nuclear factor kappa B activation in the kidney with ureteral obstruction. 9328931 1997
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.200 Biomarker phenotype RGD Expression of LFA-1 (CD11a/CD18) and ICAM-1 (CD54) in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction. 10930117 2000
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.200 Biomarker phenotype RGD Time course of cytokine mRNA expression in kidneys of rats with unilateral ureteral obstruction. 10644908 2000
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.200 Therapeutic phenotype RGD Upregulated expression of transforming growth factor-beta, type IV collagen, and plasminogen activator inhibitor-1 mRNA are decreased after release of unilateral ureteral obstruction. 12365557 2002
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.200 Biomarker phenotype RGD Plasminogen activator inhibitor-1 and tissue-type plasminogen activator are up-regulated during unilateral ureteral obstruction in adult rats. 11832778 2002
Entrez Id: 2335
Gene Symbol: FN1
FN1
0.200 Biomarker phenotype RGD Fibronectin splice variants--prognostic markers for the stage of renal interstitial fibrosis in the rat. 12218318 2002
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
0.200 Biomarker phenotype RGD Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. 12787392 2003
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.200 Biomarker phenotype RGD [Renoprotective effects of nonselective endothelin receptor antagonist bosentan on rats with interstitial fibrosis following unilateral ureteral obstruction]. 12887768 2003
Entrez Id: 2702
Gene Symbol: GJA5
GJA5
0.200 Biomarker phenotype RGD Expression of connexins in the normal and obstructed developing kidney. 12644912 2003
Entrez Id: 4060
Gene Symbol: LUM
LUM
0.200 Biomarker phenotype RGD Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. 12787392 2003
Entrez Id: 2701
Gene Symbol: GJA4
GJA4
0.200 Biomarker phenotype RGD Expression of connexins in the normal and obstructed developing kidney. 12644912 2003
Entrez Id: 10804
Gene Symbol: GJB6
GJB6
0.200 Biomarker phenotype RGD Expression of connexins in the normal and obstructed developing kidney. 12644912 2003
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.200 Biomarker phenotype RGD Effect of UUO on D1aR expression reveals a link among dopamine, transforming growth factor-beta, and nitric oxide. 14612384 2004
Entrez Id: 5062
Gene Symbol: PAK2
PAK2
0.200 Biomarker phenotype RGD Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. 15629889 2005
Entrez Id: 25
Gene Symbol: ABL1
ABL1
0.200 Biomarker phenotype RGD Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. 15629889 2005
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
0.200 Biomarker phenotype RGD Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction. 17475897 2007
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
0.200 Biomarker phenotype RGD Expression and significance of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction. 17583485 2007
Entrez Id: 384
Gene Symbol: ARG2
ARG2
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 383
Gene Symbol: ARG1
ARG1
0.200 Biomarker phenotype RGD Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats. 18552509 2008
Entrez Id: 6498
Gene Symbol: SKIL
SKIL
0.200 Biomarker phenotype RGD [Effect of tetramethylpyrazine on expression of Smad7 and SnoN in rats with UUO]. 19382458 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
0.200 Biomarker phenotype RGD Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats. 19541932 2009
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.200 Biomarker phenotype RGD Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. 19223006 2009
Entrez Id: 554
Gene Symbol: AVPR2
AVPR2
0.200 Biomarker phenotype RGD Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. 18971210 2009
Entrez Id: 112
Gene Symbol: ADCY6
ADCY6
0.200 Biomarker phenotype RGD Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. 18971210 2009