Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 842
Gene Symbol: CASP9
CASP9
0.200 Therapeutic phenotype RGD Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides. 29781318 2018
Entrez Id: 840
Gene Symbol: CASP7
CASP7
0.200 Therapeutic phenotype RGD Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides. 29781318 2018
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.200 Therapeutic phenotype RGD Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides. 29781318 2018
Entrez Id: 142
Gene Symbol: PARP1
PARP1
0.200 Therapeutic phenotype RGD Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides. 29781318 2018
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
0.200 Therapeutic phenotype RGD Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression. 28063381 2017
Entrez Id: 140823
Gene Symbol: ROMO1
ROMO1
0.200 Biomarker phenotype RGD Reactive oxygen species modulator 1 regulates oxidative stress and induces renal and pulmonary fibrosis in a unilateral ureteral obstruction rat model and in HK‑2 cells. 28791399 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.200 Therapeutic phenotype RGD Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression. 28063381 2017
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
0.200 Therapeutic phenotype RGD Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. 25707520 2015
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.200 Therapeutic phenotype RGD Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. 25707520 2015
Entrez Id: 1573
Gene Symbol: CYP2J2
CYP2J2
0.200 Biomarker phenotype RGD Macrophage epoxygenase determines a profibrotic transcriptome signature. 25840911 2015
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
0.200 Therapeutic phenotype RGD Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. 25707520 2015
Entrez Id: 1072
Gene Symbol: CFL1
CFL1
0.200 Biomarker phenotype RGD Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy. 24761003 2014
Entrez Id: 2671
Gene Symbol: GFER
GFER
0.200 Biomarker phenotype RGD Augmenter of liver regeneration ameliorates renal fibrosis in rats with obstructive nephropathy. 24844766 2014
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
0.200 Biomarker phenotype RGD Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress. 23314838 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.200 Therapeutic phenotype RGD Effect of lisinopril on renal tissue damage in unilateral ureteral obstruction in rats. 21667191 2012
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 207
Gene Symbol: AKT1
AKT1
0.200 Biomarker phenotype RGD The role of autophagy in unilateral ureteral obstruction rat model. 22085202 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.200 Biomarker phenotype RGD The effects of dietary fish oil on inflammation, fibrosis and oxidative stress associated with obstructive renal injury in rats. 21370451 2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.200 Biomarker phenotype RGD Interferon-γ improves renal interstitial fibrosis and decreases intrarenal vascular resistance of hydronephrosis in an animal model. 21216449 2011
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
0.200 Biomarker phenotype RGD The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO). 20734248 2011
Entrez Id: 847
Gene Symbol: CAT
CAT
0.200 Biomarker phenotype RGD Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat. 21305585 2011
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.200 Biomarker phenotype RGD The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO). 20734248 2011
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
0.200 Biomarker phenotype RGD A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. 20660018 2010
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.200 Biomarker phenotype RGD A sensitive short-term evaluation of antifibrotic effects using newly established type I collagen reporter transgenic rats. 20660018 2010
Entrez Id: 6498
Gene Symbol: SKIL
SKIL
0.200 Biomarker phenotype RGD [Effect of tetramethylpyrazine on expression of Smad7 and SnoN in rats with UUO]. 19382458 2009