×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.100
Biomarker
disease
HPO
×
Entrez Id:
4221
Gene Symbol:
MEN1
MEN1
0.100
Biomarker
disease
HPO
×
Entrez Id:
1030
Gene Symbol:
CDKN2B
CDKN2B
0.100
Biomarker
disease
HPO
×
Entrez Id:
1026
Gene Symbol:
CDKN1A
CDKN1A
0.100
Biomarker
disease
HPO
×
Entrez Id:
1031
Gene Symbol:
CDKN2C
CDKN2C
0.100
Biomarker
disease
HPO
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
0.170
AlteredExpression
disease
LHGDN
Absence of gene mutations in KIT-positive thymic epithelial tumors.
18486988
2008
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.100
GeneticVariation
disease
LHGDN
EGFR protein was expressed in 71% of the thymomas and 53% of the thymic carcinomas.
18448188
2008
×
Entrez Id:
1493
Gene Symbol:
CTLA4
CTLA4
0.060
GeneticVariation
disease
LHGDN
The unusual disease association with a CTLA4high genotype implies a unique pathogenesis of paraneoplastic MG, with high CTLA4 levels possibly supporting the nontolerogenic selection of CD4+ T cells in MG-associated thymomas .
16178018
2005
×
Entrez Id:
8456
Gene Symbol:
FOXN1
FOXN1
0.040
Biomarker
disease
LHGDN
Foxn1 was diffusely expressed in nuclear staining in all cases of type B thymoma and all but 1 case of type A thymoma , whereas the expression was generally focal in thymic carcinoma (76%).
17592270
2007
×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
0.030
GeneticVariation
disease
LHGDN
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis.
16437561
2006
×
Entrez Id:
2597
Gene Symbol:
GAPDH
GAPDH
0.030
AlteredExpression
disease
LHGDN
Cten mRNA expression is correlated with tumor progression in thymoma.
15001839
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
0.020
AlteredExpression
disease
LHGDN
Furthermore, additional cases of thymomas and thymic carcinomas were analyzed by COX-2 Western immunoblot analysis and were compared to normal thymi.
16823844
2006
×
Entrez Id:
84951
Gene Symbol:
TNS4
TNS4
0.010
AlteredExpression
disease
LHGDN
Cten mRNA expression is correlated with tumor progression in thymoma.
15001839
2004
×
Entrez Id:
3593
Gene Symbol:
IL12B
IL12B
0.010
AlteredExpression
disease
LHGDN
Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma.
16574246
2006
×
Entrez Id:
1145
Gene Symbol:
CHRNE
CHRNE
0.010
AlteredExpression
disease
LHGDN
The greater abundance of mRNA for AChR epsilon-subunit than for other subunits suggests that the AChR epsilon-subunit may play a distinctive role in autosensitization in MG-associated thymomas , particularly those of type A or AB.
18657869
2008
×
Entrez Id:
8626
Gene Symbol:
TP63
TP63
0.010
Biomarker
disease
LHGDN
All thymomas (including thymic carcinomas) were positive for p63 regardless of type.
17276940
2007
×
Entrez Id:
3880
Gene Symbol:
KRT19
KRT19
0.010
AlteredExpression
disease
LHGDN
Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma.
15870932
2005
×
Entrez Id:
4065
Gene Symbol:
LY75
LY75
0.010
Biomarker
disease
LHGDN
CD205 cytoplasmic expression in the form of coarse granular staining with membranous accentuation was strong and diffuse in all cases of type B thymoma (100%), and a majority of type A thymoma (89%), and focal with variable intensity in thymic carcinoma (59%).
17592270
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.360
Biomarker
disease
CTD_human
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
24974848
2014
×
Entrez Id:
8314
Gene Symbol:
BAP1
BAP1
0.310
Biomarker
disease
CTD_human
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
24974848
2014
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.310
Biomarker
disease
CTD_human
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
24974848
2014
×
Entrez Id:
1540
Gene Symbol:
CYLD
CYLD
0.300
Biomarker
disease
CTD_human
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
24974848
2014
×
Entrez Id:
55193
Gene Symbol:
PBRM1
PBRM1
0.300
Biomarker
disease
CTD_human
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.
24974848
2014
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
0.170
CausalMutation
disease
CLINVAR
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation.
15930355
2005
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
0.170
CausalMutation
disease
CLINVAR
Promising efficacy of sorafenib in a relapsed thymic carcinoma with C-KIT exon 11 deletion mutation.
20970876
2011