Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100505887
Gene Symbol: LINC01672
LINC01672
0.010 Biomarker phenotype BEFREE Fasting serum samples were analyzed with a targeted NMR approach in early pregnancy (median: 14.3 weeks of gestation). 31529056 2020
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
0.010 AlteredExpression phenotype BEFREE Peroxisome proliferator-activated receptor alpha regulates the expression of the immune response mediators in the porcine endometrium during the estrous cycle and early pregnancy. 31732996 2020
Entrez Id: 8404
Gene Symbol: SPARCL1
SPARCL1
0.010 AlteredExpression phenotype BEFREE Villous specimens were obtained from 31 women with spontaneous abortion and 31 women with normal early pregnancy to determine the expression of SPARCL1. 31675488 2020
Entrez Id: 60676
Gene Symbol: PAPPA2
PAPPA2
0.010 Biomarker phenotype BEFREE Pregnancy-associated plasma protein-A2 also shows promise as a pre-screening biomarker with the potential to reduce the need for performing oral glucose tolerance tests in early pregnancy. 31340069 2020
Entrez Id: 658
Gene Symbol: BMPR1B
BMPR1B
0.010 AlteredExpression phenotype BEFREE The qPCR and immunoblotting studies revealed that BMP2, BMPR1A, BMPR1B, and BMPR2 mRNA level was significantly (p < 0.05) upregulated during early pregnancy in COTs while in CARs it was significantly upregulated (p < 0.05) during all the stages of pregnancy.BMP4 mRNA level was significantly upregulated (p < 0.05) during early pregnancy in COTs as well as in CARs. 31445010 2020
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A
0.010 AlteredExpression phenotype BEFREE The qPCR and immunoblotting studies revealed that BMP2, BMPR1A, BMPR1B, and BMPR2 mRNA level was significantly (p < 0.05) upregulated during early pregnancy in COTs while in CARs it was significantly upregulated (p < 0.05) during all the stages of pregnancy.BMP4 mRNA level was significantly upregulated (p < 0.05) during early pregnancy in COTs as well as in CARs. 31445010 2020
Entrez Id: 55770
Gene Symbol: EXOC2
EXOC2
0.010 Biomarker phenotype BEFREE SEC5, a component of the exocyst complex, plays important roles in cell survival and migration, but its role in early pregnancy has not been reported. 31705793 2020
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
0.010 Biomarker phenotype BEFREE Microbial diversity in pregnant patients with IBD was reduced compared with that in healthy women, and significant differences existed between patients with UC and CD in early pregnancy. 31167813 2020
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
0.010 Biomarker phenotype BEFREE In the present study, we described the potential role of porcine CCL5 in embryo implantation and fetal-maternal environment during early pregnancy. 31563460 2020
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
0.010 AlteredExpression phenotype BEFREE The qPCR and immunoblotting studies revealed that BMP2, BMPR1A, BMPR1B, and BMPR2 mRNA level was significantly (p < 0.05) upregulated during early pregnancy in COTs while in CARs it was significantly upregulated (p < 0.05) during all the stages of pregnancy.BMP4 mRNA level was significantly upregulated (p < 0.05) during early pregnancy in COTs as well as in CARs. 31445010 2020
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L
0.010 Biomarker phenotype BEFREE In addition to well established mechanisms in one-carbon metabolism, formate may play an important role in early pregnancy by preventing the onset of neural tube defects in sensitive strains of mice, including mice with deficiencies in MTHFD1L, the glycine cleavage system and the mitochondrial folate transporter. 31688093 2020
Entrez Id: 1236
Gene Symbol: CCR7
CCR7
0.010 Biomarker phenotype BEFREE Our results indicated that CCL21 and CCR7 are increased in the glandular (GE) and luminal epithelium (LE) of the endometrium during early pregnancy, compared to estrous pigs. 30711450 2019
Entrez Id: 406992
Gene Symbol: MIR210
MIR210
0.010 Biomarker phenotype BEFREE The objectives of this study were to identify targets of miR-210 in first trimester primary extravillous trophoblasts (EVTs) and to investigate functional pathways altered by elevated placental miR-210 during early pregnancy. 31263422 2019
Entrez Id: 7038
Gene Symbol: TG
TG
0.010 Biomarker phenotype BEFREE THs and TAs including thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TgAb) were measured in maternal blood during early pregnancy (median 11 gestational weeks), and in cord blood at birth. 31518930 2019
Entrez Id: 58506
Gene Symbol: SCAF1
SCAF1
0.010 Biomarker phenotype BEFREE To provide first insights into the contribution of SR-A to endometrial physiology, we analysed the expression and regulation of all members of SR-A (SR-A1, SR-A3-SR-A6) during the oestrous cycle and early pregnancy in cattle. 30922439 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
0.010 Biomarker phenotype BEFREE This is the first study on the role of the PD-1/PD-L1 axis in macrophage polarization during early pregnancy; such exploration enhances our understanding of the physiology of early pregnancy. 30500923 2019
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.010 Biomarker phenotype BEFREE THs and TAs including thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TgAb) were measured in maternal blood during early pregnancy (median 11 gestational weeks), and in cord blood at birth. 31518930 2019
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.010 AlteredExpression phenotype BEFREE Expression of THBS1 is also downregulated by pregnancy recognition signals to maintain the CL during early pregnancy. 30566900 2019
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
0.010 Biomarker phenotype BEFREE The distinct accumulation of NDRG1 protein signals was observed in the primary decidual zone adjacent to the implanting embryo during early pregnancy. 31339191 2019
Entrez Id: 7474
Gene Symbol: WNT5A
WNT5A
0.010 Biomarker phenotype BEFREE In summary, these results suggested that BaP exposure during early pregnancy activates WNT5A/β-catenin signaling pathway, which inhibits the endometrial cell apoptosis and potentially destroys endometrial function. 30443902 2019
Entrez Id: 11009
Gene Symbol: IL24
IL24
0.010 Biomarker phenotype BEFREE The aim of our study was to investigate the function and significance of IL-24 and its receptor in the coordination between DSCs and natural killer cells (NK) in early pregnancy. 30903677 2019
Entrez Id: 56891
Gene Symbol: LGALS14
LGALS14
0.010 AlteredExpression phenotype BEFREE In conclusion, these results show that Gal-13 and Gal-14 already provide an immunoprivileged environment at the maternal-fetal interface during early pregnancy, and their reduced expression is related to miscarriages. 31275299 2019
Entrez Id: 5008
Gene Symbol: OSM
OSM
0.010 AlteredExpression phenotype BEFREE Oncostatin M expression in the mouse uterus during early pregnancy promotes embryo implantation and decidualization. 31155707 2019
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
0.010 AlteredExpression phenotype BEFREE The mRNA expression of cytochrome P450 family 11 subfamily A member 1 and hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 was analyzed using real-time PCR, while progesterone concentration in culture medium was assessed by radioimmunoassay.Dynamic changes of prostacyclin synthase and prostacyclin receptor expression were observed in porcine luteal tissue during the estrous cycle and early pregnancy. 30481284 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
0.010 AlteredExpression phenotype BEFREE Expression of galectin-3 and apoptosis in placental villi from patients with missed abortion during early pregnancy. 30906454 2019