Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype CTD_human Genetic diagnosis in infertile men with numerical and constitutional sperm abnormalities. 18554162 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype CTD_human Genotyping of Israeli infertile men with idiopathic oligozoospermia. 12220434 2002
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype CTD_human Transcriptional profiling of luteinizing hormone receptor-deficient mice before and after testosterone treatment provides insight into the hormonal control of postnatal testicular development and Leydig cell differentiation. 20164437 2010
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 GeneticVariation phenotype BEFREE Non-linear association between androgen receptor CAG repeat length and risk of male subfertility--a meta-analysis. 20579136 2011
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype BEFREE In this study we investigated the association of male subfertility with the length of CAG repeats in the androgen receptor. 11792931 2002
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.310 Biomarker phenotype CTD_human Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility. 16861746 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.310 GeneticVariation phenotype BEFREE The data suggest that the C677T MTHFR polymorphism is not a risk factor for idiopathic male subfertility in an Algerian population. 22928696 2012
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		0.310 GeneticVariation phenotype BEFREE To investigate the association between the human 8-oxoguanine DNA glycosylase 1 (hOGG1) gene Ser326Cys polymorphism and male subfertility in Taiwanese patients with varicocele, we made a prospective study. 29582449 2018
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.310 AlteredExpression phenotype BEFREE A missense mutation in SLC26A3 is associated with human male subfertility and impaired activation of CFTR. 29079751 2017
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.310 Biomarker phenotype CTD_human Novel CFTR missense mutations in Brazilian patients with congenital absence of vas deferens: counseling issues. 17823699 2007
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		0.310 Biomarker phenotype CTD_human OGG1 Ser326Cys polymorphism interacts with cigarette smoking to increase oxidative DNA damage in human sperm and the risk of male infertility. 23376476 2013
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.310 Biomarker phenotype CTD_human Genetic diagnosis in infertile men with numerical and constitutional sperm abnormalities. 18554162 2008
Entrez Id: 79730
Gene Symbol: NSUN7
NSUN7 		0.300 Biomarker phenotype CTD_human Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases. 17442852 2007
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker phenotype CTD_human Genetic variants in nitric oxide synthase genes and the risk of male infertility in a Chinese population: a case-control study. 25517965 2014
Entrez Id: 346562
Gene Symbol: GNAT3
GNAT3 		0.300 Biomarker phenotype CTD_human Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility. 23818598 2013
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.300 Biomarker phenotype CTD_human Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders. 30245210 2018
Entrez Id: 5887
Gene Symbol: RAD23B
RAD23B 		0.300 Biomarker phenotype CTD_human Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B. 11809813 2002
Entrez Id: 387712
Gene Symbol: ENO4
ENO4 		0.300 Biomarker phenotype CTD_human Disruption of a spermatogenic cell-specific mouse enolase 4 (eno4) gene causes sperm structural defects and male infertility. 23446454 2013
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.300 Biomarker phenotype CTD_human Possible effects of metallosis on spermatozoal apoptotic genes expression in individuals with intramedullary nailing prosthesis. 24723216 2014
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1 		0.300 Biomarker phenotype CTD_human Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. 15890676 2005
Entrez Id: 2488
Gene Symbol: FSHB
FSHB 		0.300 Biomarker phenotype CTD_human Endocrinology of male infertility. 387166 1979
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function. 23213263 2012
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Ex3αERKO male infertility phenotype recapitulates the αERKO male phenotype. 20833731 2010
Entrez Id: 3948
Gene Symbol: LDHC
LDHC 		0.300 Biomarker phenotype CTD_human Lactate dehydrogenase C and energy metabolism in mouse sperm. 21565994 2011
Entrez Id: 3948
Gene Symbol: LDHC
LDHC 		0.300 Biomarker phenotype CTD_human Glycolysis and mitochondrial respiration in mouse LDHC-null sperm. 23486916 2013