Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2488
Gene Symbol: FSHB
FSHB 		0.300 Biomarker phenotype CTD_human Endocrinology of male infertility. 387166 1979
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.300 Biomarker phenotype CTD_human Endocrinology of male infertility. 387166 1979
Entrez Id: 3237
Gene Symbol: HOXD11
HOXD11 		0.300 Biomarker phenotype CTD_human Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. 7925020 1994
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker phenotype CTD_human Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. 8642790 1996
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.300 Biomarker phenotype CTD_human Association of molecular variants of luteinizing hormone with male infertility. 10739843 2000
Entrez Id: 1618
Gene Symbol: DAZL
DAZL 		0.010 Biomarker phenotype BEFREE To study the role of the autosomal candidate gene DAZLA (Deleted in AZoospermia Like Autosome) in male subfertility. 11499325 2001
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype BEFREE In this study we investigated the association of male subfertility with the length of CAG repeats in the androgen receptor. 11792931 2002
Entrez Id: 5887
Gene Symbol: RAD23B
RAD23B 		0.300 Biomarker phenotype CTD_human Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B. 11809813 2002
Entrez Id: 367
Gene Symbol: AR
AR 		0.320 Biomarker phenotype CTD_human Genotyping of Israeli infertile men with idiopathic oligozoospermia. 12220434 2002
Entrez Id: 1760
Gene Symbol: DMPK
DMPK 		0.010 GeneticVariation phenotype BEFREE The number of CTG repeats in the normal or mutational range of DM1PK gene is associated with neither idiopathic male subfertility nor with clinical characteristics of male subfertility. 15284213 2004
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.300 Biomarker phenotype CTD_human Hypogonadism in a patient with a mutation in the luteinizing hormone beta-subunit gene. 15602022 2004
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1 		0.300 Biomarker phenotype CTD_human Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. 15890676 2005
Entrez Id: 867
Gene Symbol: CBL
CBL 		0.300 Biomarker phenotype CTD_human Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl. 16301331 2005
Entrez Id: 1811
Gene Symbol: SLC26A3
SLC26A3 		0.040 Biomarker phenotype BEFREE Disruption of the SLC26A3-mediated anion transport is associated with male subfertility. 16412765 2006
Entrez Id: 1811
Gene Symbol: SLC26A3
SLC26A3 		0.040 Biomarker phenotype BEFREE Tissue-specific co-expression with CFTR and NHE3 supports diverse functions of SLC26A3 and may have an impact on pathophysiology of male subfertility both in CLD and in cystic fibrosis (CF), as well as spermatoceles. 16421216 2006
Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3 		0.010 AlteredExpression phenotype BEFREE Tissue-specific co-expression with CFTR and NHE3 supports diverse functions of SLC26A3 and may have an impact on pathophysiology of male subfertility both in CLD and in cystic fibrosis (CF), as well as spermatoceles. 16421216 2006
Entrez Id: 1811
Gene Symbol: SLC26A3
SLC26A3 		0.040 Biomarker phenotype BEFREE A putative role of a primary anion exchange defect of SLC26A3 in male subfertility and the decline of renal function due to chronic dehydration deserve further characterization. 16641574 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.310 Biomarker phenotype CTD_human Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility. 16861746 2006
Entrez Id: 4548
Gene Symbol: MTR
MTR 		0.300 Biomarker phenotype CTD_human Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility. 16861746 2006
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		0.300 Biomarker phenotype CTD_human Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility. 16861746 2006
Entrez Id: 6795
Gene Symbol: AURKC
AURKC 		0.300 Biomarker phenotype CTD_human Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility. 17435757 2007
Entrez Id: 79730
Gene Symbol: NSUN7
NSUN7 		0.300 Biomarker phenotype CTD_human Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases. 17442852 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.310 Biomarker phenotype CTD_human Novel CFTR missense mutations in Brazilian patients with congenital absence of vas deferens: counseling issues. 17823699 2007
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.300 Biomarker phenotype CTD_human Alpers syndrome with prominent white matter changes. 17923349 2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP 		0.300 Biomarker phenotype CTD_human Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. 17961124 2008