Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
THPO P40225 thrombopoietin 0.20 0.513 0.692
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
ATN1 P54259 atrophin 1 1.00 0.409 0.885
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 1.00 0.486 0.846