Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KITLG P21583 KIT ligand 0.85 0.473 0.885
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MIR150 microRNA 150 0.455 0.808
MIR223 microRNA 223 0.433 0.808
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692