Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SCNN1A P37088 sodium channel epithelial 1 subunit alpha Ion channel 1.1E-11 0.601 0.577
CH25H O95992 cholesterol 25-hydroxylase Enzyme 0.23 0.663 0.577
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
MIR505 microRNA 505 0.603 0.577
USF1 P22415 upstream transcription factor 1 2.4E-02 0.592 0.692
PEA15 Q15121 proliferation and apoptosis adaptor protein 15 0.79 0.553 0.692
FTH1 P02794 ferritin heavy chain 1 Storage 0.14 0.559 0.731
TNFRSF10C O14798 TNF receptor superfamily member 10c 3.2E-06 0.578 0.731
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
CXCR1 P25024 C-X-C motif chemokine receptor 1 G-protein coupled receptor 3.0E-07 0.508 0.769
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
SP1 P08047 Sp1 transcription factor Nucleic acid binding 1.00 0.493 0.769
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769
MVP Q14764 major vault protein Nucleic acid binding 6.8E-08 0.512 0.769
LINC01194 long intergenic non-protein coding RNA 1194 0.470 0.769
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
OCA2 Q04671 OCA2 melanosomal transmembrane protein 2.9E-13 0.539 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
TNFSF4 P23510 TNF superfamily member 4 Signaling 4.9E-02 0.540 0.808
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
ACSS2 Q9NR19 acyl-CoA synthetase short chain family member 2 Enzyme 1.1E-13 0.506 0.808
SEMA6A Q9H2E6 semaphorin 6A Signaling 1.00 0.486 0.808