Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
C4BPA P04003 complement component 4 binding protein alpha 0.46 0.556 0.846
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
IL4R P24394 interleukin 4 receptor Receptor 2.3E-04 0.474 0.846
PDE4A P27815 phosphodiesterase 4A 0.98 0.523 0.846
SLC22A3 O75751 solute carrier family 22 member 3 Transporter 7.8E-10 0.531 0.846
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
CD28 P10747 CD28 molecule 0.36 0.436 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
GCLC P48506 glutamate-cysteine ligase catalytic subunit Enzyme 0.43 0.509 0.885
CFH P08603 complement factor H 0.86 0.441 0.885
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885