Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LINC01194 long intergenic non-protein coding RNA 1194 0.470 0.769
MIR505 microRNA 505 0.603 0.577
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TNFRSF10C O14798 TNF receptor superfamily member 10c 3.2E-06 0.578 0.731
SLC22A3 O75751 solute carrier family 22 member 3 Transporter 7.8E-10 0.531 0.846
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
CH25H O95992 cholesterol 25-hydroxylase Enzyme 0.23 0.663 0.577
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
FTH1 P02794 ferritin heavy chain 1 Storage 0.14 0.559 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
C4BPA P04003 complement component 4 binding protein alpha 0.46 0.556 0.846