Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
SP1 P08047 Sp1 transcription factor Nucleic acid binding 1.00 0.493 0.769
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
CFH P08603 complement factor H 0.86 0.441 0.885
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
TXN P10599 thioredoxin 0.20 0.447 0.885
CD28 P10747 CD28 molecule 0.36 0.436 0.885
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
USF1 P22415 upstream transcription factor 1 2.4E-02 0.592 0.692
TNFSF4 P23510 TNF superfamily member 4 Signaling 4.9E-02 0.540 0.808