Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACSS2 Q9NR19 acyl-CoA synthetase short chain family member 2 Enzyme 1.1E-13 0.506 0.808
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
C4BPA P04003 complement component 4 binding protein alpha 0.46 0.556 0.846
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CFH P08603 complement factor H 0.86 0.441 0.885
CH25H O95992 cholesterol 25-hydroxylase Enzyme 0.23 0.663 0.577
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR1 P25024 C-X-C motif chemokine receptor 1 G-protein coupled receptor 3.0E-07 0.508 0.769
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923