Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
TMED9 Q9BVK6 transmembrane p24 trafficking protein 9 Transporter 6.0E-03 0.666 0.538
NEFM P07197 neurofilament medium 1.8E-02 0.674 0.577
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
HRES1 P13985 HTLV-1 related endogenous sequence 0.636 0.615
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
TPPP O94811 tubulin polymerization promoting protein Cellular structure 0.20 0.570 0.692
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NEFL P07196 neurofilament light 0.488 0.769
PFN1 P07737 profilin 1 0.73 0.565 0.769
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
HNRNPA2B1 P22626 heterogeneous nuclear ribonucleoprotein A2/B1 1.00 0.566 0.808
RAN P62826 RAN, member RAS oncogene family Enzyme modulator 0.98 0.576 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
CDK5R1 Q15078 cyclin dependent kinase 5 regulatory subunit 1 Enzyme modulator 0.91 0.529 0.808