Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HRES1 P13985 HTLV-1 related endogenous sequence 0.636 0.615
NEFL P07196 neurofilament light 0.488 0.769
MIR206 microRNA 206 0.477 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
TMED9 Q9BVK6 transmembrane p24 trafficking protein 9 Transporter 6.0E-03 0.666 0.538
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFM P07197 neurofilament medium 1.8E-02 0.674 0.577
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731