Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
MIR206 microRNA 206 0.477 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
NEFL P07196 neurofilament light 0.488 0.769
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769