Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR206 microRNA 206 0.477 0.846
TPPP O94811 tubulin polymerization promoting protein Cellular structure 0.20 0.570 0.692
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
NEFL P07196 neurofilament light 0.488 0.769
NEFM P07197 neurofilament medium 1.8E-02 0.674 0.577
PFN1 P07737 profilin 1 0.73 0.565 0.769
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
HRES1 P13985 HTLV-1 related endogenous sequence 0.636 0.615
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
HNRNPA2B1 P22626 heterogeneous nuclear ribonucleoprotein A2/B1 1.00 0.566 0.808
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885