|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined associations between the endothelial nitric oxide synthase (eNOS) gene Glu-298-->Asp (894G-->T) mutation and the occurrence and severity of angiographically defined coronary artery disease (CAD). eNOS mediates basal vascular wall nitric oxide production, and altered nitric oxide production has been implicated in atherosclerosis.
|
10475066 |
1999 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In summary, results in our study do not support the hypothesis that the rs4986790 (+896A>G, Asp299Gly) TLR4 variant may influence predisposition for subclinical atherosclerosis and clinically evident CV disease in RA patients.
|
22360682 |
2012 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
These findings indicated that TLR4 Asp299Gly polymorphism may not play a role in AS development.
|
22857799 |
2012 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The G allele of the Toll-like receptor 4 (TLR-4) gene Asp299Gly polymorphism has been previously associated with decreased development of atherosclerosis and with lower risk of myocardial infractions.
|
17996871 |
2008 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To explore a potential atheroprotective effect, we studied the association between the Asp299Gly polymorphism and atherosclerosis in hypertensive patients undergoing angiography for suspected renovascular disease.
|
17587646 |
2007 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The purpose of this study was to investigate the role of a common Asp299Gly polymorphism of the TLR-4 gene in atherosclerosis.
|
17101559 |
2006 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We examined toll-like receptor 4 (TLR4) as a candidate gene for AMD susceptibility because: (i) the TLR4 gene is located on chromosome 9q32-33, a region exhibiting evidence of linkage to AMD in three independent reports; (ii) the TLR4-D299G variant is associated with reduced risk of atherosclerosis, a chronic inflammatory disease with subendothelial accumulation; (iii) the TLR4 is not only a key mediator of proinflammatory signaling pathways but also linked to regulation of cholesterol efflux and (iv) the TLR4 participates in phagocytosis of photoreceptor outer segments by the RPE.
|
15829498 |
2005 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The presence of the Asp299Gly allele of the TLR4 gene does not seem to exert a major influence on the progression of atherosclerosis in patients with FH.
|
14764071 |
2004 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
1400 participants (mean age: 63 years, 31% female) in the Southampton Atherosclerosis Study were genotyped for the TLR4 Asp299Gly polymorphism using the tetra-primer PCR method.
|
12957699 |
2003 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The Asp299Gly TLR4 polymorphism, which attenuates receptor signaling and diminishes the inflammatory response to gram-negative pathogens, is associated with a decreased risk of atherosclerosis.
|
12124407 |
2002 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The rs1805193, rs5361, and rs5355 single nucleotide polymorphisms in the E-selectin gene (SEL-E) are associated with subclinical atherosclerosis: The Genetics of Atherosclerotic Disease (GEA) Mexican study.
|
30501958 |
2019 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient populations with atherosclerosis or restenosis.
|
16908800 |
2006 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient groups with atherosclerosis or restenosis.
|
15546947 |
2005 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The aim of this study was to assess E-selectin Ser128Arg polymorphism in subjects with clinical and instrumental evidence of atherosclerosis and to analyze the correlations with clinical severity.
|
15179350 |
2004 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Relationships between the E-selectin S128R polymorphism and coronary artery calcification (CAC), a marker of atherosclerosis detected with noninvasive electron beam computed tomography, were examined in 294 asymptomatic women aged 40--88 years and 314 asymptomatic men aged 30--80 years from the Epidemiology of Coronary Artery Calcification Study.
|
11466561 |
2001 |
|
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Functional characterization of atherosclerosis-associated Ser128Arg and Leu554Phe E-selectin mutations.
|
10430030 |
1999 |
|
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Q192R was more strongly associated with PCOS than previously suggested atherosclerosis risk markers.
|
30900463 |
2019 |
|
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The Q192R (rs662; A/G) polymorphism, which results in the glutamine to arginine substitution at position 192, of the PON1 gene has been linked to increased atherosclerosis risk in several but not all population studies.
|
23625196 |
2013 |
|
rs1458766475
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Serum PON-1 activity but not Q192R polymorphism is related to the extent of atherosclerosis.
|
22188760 |
2012 |
|
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
|
21982484 |
2011 |
|
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In this study, we enrolled 1746 type 2 diabetic subjects, determined 4 common genetic variants related to oxidative stress (glutamate-cysteine ligase modifier subunit (GCLM) C-588T, myeloperoxidase G-463A, human paraoxonase 1 Gln192Arg and NAD(P)H oxidase p22phox C242T polymorphisms), and measured carotid intima-media thickness (IMT) as a surrogate marker for atherosclerosis.
|
19126404 |
2009 |
|
rs1458766475
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient populations with atherosclerosis or restenosis.
|
16908800 |
2006 |
|
rs1458766475
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient groups with atherosclerosis or restenosis.
|
15546947 |
2005 |