Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11747270
rs11747270
0.010 GeneticVariation BEFREE IRGM rs4958847 and rs11747270 increased the risk of developing arthritis in patients with CD. 31654602

2020

dbSNP: rs4958847
rs4958847
0.010 GeneticVariation BEFREE IRGM rs4958847 and rs11747270 increased the risk of developing arthritis in patients with CD. 31654602

2020

dbSNP: rs10036748
rs10036748
0.010 GeneticVariation BEFREE Patients with psoriasis with TT genotype of rs10036748 in TNIP1, with lower BMI, without arthritis will achieve a better response to MTX. 31020648

2019

dbSNP: rs1544410
rs1544410
VDR
0.010 GeneticVariation BEFREE The clinical characteristics of BD patients were evaluated and patients with ocular lesions had a higher percentage of rs1544410 A alleles (p = 0.004), and patients with oral aphthous lesions, a positive pathergy tests, and arthritis had more rs2228570 C alleles than patients without these clinical findings (respectively, p < 0.001, p = 0.021, p = 0.045). 30730049

2019

dbSNP: rs1562444
rs1562444
0.010 GeneticVariation BEFREE Case-only analysis showed associations of rs2165667 and rs1562444 with arthritis, rs10830962 with malar rash, rs3760138 with immunological abnormality, and rs8150 with hematological abnormality. 31815152

2019

dbSNP: rs2165667
rs2165667
0.010 GeneticVariation BEFREE Case-only analysis showed associations of rs2165667 and rs1562444 with arthritis, rs10830962 with malar rash, rs3760138 with immunological abnormality, and rs8150 with hematological abnormality. 31815152

2019

dbSNP: rs2228570
rs2228570
VDR
0.010 GeneticVariation BEFREE The clinical characteristics of BD patients were evaluated and patients with ocular lesions had a higher percentage of rs1544410 A alleles (p = 0.004), and patients with oral aphthous lesions, a positive pathergy tests, and arthritis had more rs2228570 C alleles than patients without these clinical findings (respectively, p < 0.001, p = 0.021, p = 0.045). 30730049

2019

dbSNP: rs224222
rs224222
0.010 GeneticVariation BEFREE Recurrent abdominal pain and arthritis/arthralgia were commonly observed in patients with M694V and R202Q mutations. 30284126

2019

dbSNP: rs2476601
rs2476601
0.010 GeneticVariation BEFREE Patients with rheumatoid arthritis (RA) or undifferentiated arthritis (UA) in the CONAART database (Argentine Consortium for Early Arthritis) were assessed for genetic risk factors for RA, specifically for HLA-DRB1 alleles and the PTPN22 rs2476601 polymorphism associated with progression to RA.This is a case-control study. 30306282

2019

dbSNP: rs3746444
rs3746444
0.010 GeneticVariation BEFREE The present study indicates that miRNA-499 rs3746444 polymorphism is associated with inflammatory arthritis susceptibility. 31223622

2019

dbSNP: rs731236
rs731236
VDR
0.010 GeneticVariation BEFREE The rs10735810, rs1544410, rs7975232, and rs731236 were associated with the onset of arthritis at both allelic and genotypic level (p < 0.01). 31011579

2019

dbSNP: rs741761
rs741761
0.010 GeneticVariation BEFREE There were differences in the genotype frequencies and allele frequencies of rs741761 between SLE patients with and without arthritis. 31394943

2019

dbSNP: rs7975232
rs7975232
VDR
0.010 GeneticVariation BEFREE The rs10735810, rs1544410, rs7975232, and rs731236 were associated with the onset of arthritis at both allelic and genotypic level (p < 0.01). 31011579

2019

dbSNP: rs10491322
rs10491322
0.010 GeneticVariation BEFREE Specifically, carriage of the rs10491322 G* allele led to a higher prevalence of arthritis in SLE patients (P = .01). 29979448

2018

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE The association between the gene polymorphisms of MTHFR (c.1298A>C and c.677C>T) and MTX toxicity in arthritis patients is confirmed. 30544400

2018

dbSNP: rs2501432
rs2501432
0.010 GeneticVariation BEFREE In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases. 29694791

2018

dbSNP: rs3024498
rs3024498
0.010 GeneticVariation BEFREE Interestingly, significant differences were detected both in the allele and genotype frequencies of rs3024498 between SLE patients with and without arthritis (P=0.002, P=0.022, respectively).There was significant difference in genotype frequency at rs3024498 between SLE patients with and without malar rash (P=0.040). 29199038

2018

dbSNP: rs35761398
rs35761398
0.010 GeneticVariation BEFREE In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases. 29694791

2018

dbSNP: rs397507444
rs397507444
0.010 GeneticVariation BEFREE The association between the gene polymorphisms of MTHFR (c.1298A>C and c.677C>T) and MTX toxicity in arthritis patients is confirmed. 30544400

2018

dbSNP: rs879761216
rs879761216
0.010 GeneticVariation BEFREE In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases. 29694791

2018

dbSNP: rs104895094
rs104895094
0.010 GeneticVariation BEFREE Arthritis was high in K695R heterozygous genotype. 28483595

2017

dbSNP: rs2234693
rs2234693
0.010 GeneticVariation BEFREE Conclusions Minor allele rs2234693-C was associated with renal and cutaneous involvement, as well as the absence of arthritis, anti-ANA and anti-RNP autoantibodies. 27681518

2017

dbSNP: rs4986790
rs4986790
0.010 GeneticVariation BEFREE A phenotypic correlation of Asp299Gly-AG genotype with arthritis in UC patients was detected (P = 0.003). 29055077

2017

dbSNP: rs7033979
rs7033979
0.010 GeneticVariation BEFREE The two arthritis-susceptible candidate SNPs, rs7775 (p.Arg324Gly) in the FRZB gene and rs7033979 in the ASPN gene, showed associations with KBD (OR = 1.568, P = 4 × 10<sup>-3</sup> and OR = 0.744, P = 8 × 10<sup>-3</sup>, respectively). 28651521

2017

dbSNP: rs771184127
rs771184127
0.010 GeneticVariation BEFREE A phenotypic correlation of Asp299Gly-AG genotype with arthritis in UC patients was detected (P = 0.003). 29055077

2017