|
rs1057519090
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1057523354
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs28936375
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs540558
|
|
|
0.010 |
GeneticVariation |
BEFREE |
94.38% of SLE patients with arthritis were belonged to the -1687C/C (rs540558) genotype.
|
24219225 |
2014 |
|
rs28940580
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Arthritis frequency was found to be lower in the patients with homozygous Met680Ile mutation.
|
10662876 |
2000 |
|
rs61752717
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Arthritis patterns in familial Mediterranean fever patients and association with M694V mutation.
|
20845072 |
2011 |
|
rs104895094
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Arthritis was high in K695R heterozygous genotype.
|
28483595 |
2017 |
|
rs61752717
|
|
|
0.100 |
GeneticVariation |
BEFREE |
M694V genotype seems to be more frequently associated with arthritis as well as with chronic arthritis than other genotypes.
|
28828621 |
2018 |
|
rs17197936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A harmful association was observed between the minor allele of rs17197936 and 2 clinical traits, count of joints with active arthritis and count of joints with pain on motion/tenderness, in patients with extended oligoarthritis.
|
25236364 |
2014 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A phenotypic correlation of Asp299Gly-AG genotype with arthritis in UC patients was detected (P = 0.003).
|
29055077 |
2017 |
|
rs771184127
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A phenotypic correlation of Asp299Gly-AG genotype with arthritis in UC patients was detected (P = 0.003).
|
29055077 |
2017 |
|
rs755622
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A second MIF promoter polymorphism comprises a G-to-C single nucleotide polymorphism (SNP) at position -173 (rs755622), which is in strong linkage disequilibrium with -794 7-CATT and is associated with arthritis clinical severity and higher serum and synovial fluid MIF levels.
|
31745872 |
2020 |
|
rs755622
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A significantly lower frequency of the G allele of rs755622 was observed in the oral aphthae, genital ulceration, hypopyon, and arthritis subgroups compared with controls (P(c) < 0.05).
|
22939113 |
2012 |
|
rs11614913
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A stratified analysis showed an association of the rs11614913 TT genotype and T allele with the arthritis subgroup of BD (P(c) = 5.3 × 10(-3), OR = 1.89; P(c) = 0.015, OR = 1.56, respectively).
|
23928854 |
2013 |
|
rs3789604
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 667 RA patients and 286 controls were genotyped for 13 PTPN22 single nucleotide polymorphisms (SNPs) by allele-specific kinetic polymerase chain reaction. rs3789604 was genotyped in an additional 410 RA and 270 UA patients participating in the Leiden early arthritis inception cohort.
|
17135225 |
2007 |
|
rs1800562
|
|
|
0.080 |
GeneticVariation |
BEFREE |
All previously undiagnosed C282Y homozygotes (35 male, 67 female) and all HFE wild-types (131 male, 160 female) with baseline and follow-up SF concentrations <1000 microg/L were assessed for HH-associated signs and symptoms including abnormal second/third metacarpophalangeal joints (MCP2/3), raised liver enzymes, hepatomegaly, and self-reported liver disease, fatigue, diabetes mellitus, and use of arthritis medication.
|
20583211 |
2010 |
|
rs3743930
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Although four of the 26 patients with E148Q/E148Q were asymptomatic at the time of evaluation, abdominal pain was seen in 77% of the patients, fever in 66%, arthralgia in 50%, arthritis in 15.4%, and vomiting in 23.8%.
|
15458961 |
2005 |
|
rs1800925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An additional SNP, rs1800925, was genotyped only in the PsA and PsC groups.
|
21613309 |
2011 |
|
rs61752717
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Arthralgia or arthritis was significantly higher in M694V carriers than in non-M694V carriers (p < 0.05).
|
18300119 |
2008 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
But, we also find miRNA-146 rs2910164 and miRNA-499 rs3746444 polymorphism are associated with inflammatory arthritis in Middle East.
|
31223622 |
2019 |
|
rs2165667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Case-only analysis showed associations of rs2165667 and rs1562444 with arthritis, rs10830962 with malar rash, rs3760138 with immunological abnormality, and rs8150 with hematological abnormality.
|
31815152 |
2019 |
|
rs1562444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Case-only analysis showed associations of rs2165667 and rs1562444 with arthritis, rs10830962 with malar rash, rs3760138 with immunological abnormality, and rs8150 with hematological abnormality.
|
31815152 |
2019 |
|
rs61752717
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Children homozygous for the M694V mutation presented at a younger age, had a higher severity score, and more commonly had arthritis.
|
12508410 |
2003 |
|
rs2234693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Conclusions Minor allele rs2234693-C was associated with renal and cutaneous involvement, as well as the absence of arthritis, anti-ANA and anti-RNP autoantibodies.
|
27681518 |
2017 |
|
rs61752717
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Fever and arthritis were determined in similar ratios to other genotypes (76% and 19%, respectively) in the M694V/M694V genotype (74% and 29%, respectively) (p > 0.50 and p > 0.20, respectively).
|
20373849 |
2010 |