|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In dementia patients, there was an association between the PITX2 loci and AF (rs2634073: odds ratio [OR] = 2.11; P = 0.025 and rs2200733: OR = 2.27; P = 0.029).
|
25494715 |
2015 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In this hypothesis-generating pilot study of predominantly Caucasian men, the effect on AF response to AAD therapy of rs10033464 at 4q25 varied based on OSA status.
|
24910551 |
2014 |
|
rs2106261
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In summary, our study investigated the role of genetic variants of ZFHX3 in AF and two SNPs (rs2106261, rs6499600) showed significant associations while rs16971436 conferred a borderline significant association with AF risk in Chinese Han populations.
|
24983873 |
2014 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Variants rs2200733 and rs7193343 are associated with a higher risk of atrial fibrillation.
|
25262128 |
2014 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
These findings suggest that the causal mechanism associated with rs2200733 is germane to both AF and Afl.
|
24237655 |
2014 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We found that a common 4q25 AF susceptibility allele (rs2200733) is associated with PR interval prolongation in patients with lone and typical AF and controls with no AF.
|
24161141 |
2014 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Common single nucleotide polymorphisms at chromosome 4q25 (rs2200733, rs10033464) are associated with both lone and typical atrial fibrillation (AF).
|
23178686 |
2013 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In multivariable analysis, the presence of any common single nucleotide polymorphism (rs2200733, rs10033464) at the 4q25 locus was an independent predictor of AF recurrence (hazard ratio 2.1; 95% confidence interval 1.21-3.30; P = .008).
|
23428961 |
2013 |
|
rs2106261
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Genetic polymorphisms in the chromosomal regions 4q25 (rs2200733) and 16q22 (rs2106261) associated with AF in genome-wide association studies were genotyped.
|
23132824 |
2013 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our findings show that a common polymorphism on chromosome 4q25 (rs2200733) is an independent predictor of AF recurrence after DCCV and point to a potential role of stratification by genotype.
|
23428961 |
2013 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our findings suggest that the rs2200733 polymorphism may hold promise as an objectively measured patient characteristic that can be used as a clinical tool for selecting patients for AF ablation.
|
23178686 |
2013 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Genetic polymorphisms in the chromosomal regions 4q25 (rs2200733) and 16q22 (rs2106261) associated with AF in genome-wide association studies were genotyped.
|
23132824 |
2013 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Variant rs2200733 on chromosome 4q25 independently confers increased risk of AF.
|
23130627 |
2013 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
None of the single nucleotide polymorphisms previously associated with AF in European populations, including rs2200733, were associated with AF in the WHI African American cohort.
|
24016508 |
2013 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In genetic association analyses, unstratified and stratified according to age of onset of AF and unaffected age >50 years, there was a highly statistically significant association between the presence of both common (rs2200733 and rs10033464) and rare variants and AF (unstratified p = 1 × 10(-8), stratified [age of onset <50 years and unaffected age >50 years] p = 7.6 × 10(-5)) (unstratified p < 0.0001, stratified [age of onset <50 years and unaffected age >50 years] p < 0.0001).
|
22818067 |
2012 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This SNP (rs10033464) was an independent predictor of AF recurrence in the discovery (39% AF recurrence) and validation (38% AF recurrence) cohorts; OR: 3.27, 95% CI: 1.7 to 6, p < 0.001 and OR: 4.3, 95% CI: 1.98 to 9.4, p < 0.001, respectively.
|
22726630 |
2012 |
|
rs2106261
|
|
T |
0.900 |
GeneticVariation |
GWASDB |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
22544366 |
2012 |
|
rs2106261
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
22544366 |
2012 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In genetic association analyses, unstratified and stratified according to age of onset of AF and unaffected age >50 years, there was a highly statistically significant association between the presence of both common (rs2200733 and rs10033464) and rare variants and AF (unstratified p = 1 × 10(-8), stratified [age of onset <50 years and unaffected age >50 years] p = 7.6 × 10(-5)) (unstratified p < 0.0001, stratified [age of onset <50 years and unaffected age >50 years] p < 0.0001).
|
22818067 |
2012 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Three SNPs, rs2200733 (4q25), rs3807989 (7p31), and rs11047543 (12p12), were associated with early-onset lone AF.
|
22336519 |
2012 |
|
rs10033464
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Both rs2200733 and rs10033464 were also associated with long-term A</span>F (hazard ratio 1.32, 95% CI 1.05 to 1.67, and hazard ratio 1.28, 95% CI 1.00 to 1.66, respectively).
|
21414601 |
2011 |
|
rs2106261
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our results indicate that rs2106261 in ZFHX3 confers a significant risk of AF in a Chinese Han population.
|
21107608 |
2011 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Both rs2200733 and rs10033464 were also associated with long-term A</span>F (hazard ratio 1.32, 95% CI 1.05 to 1.67, and hazard ratio 1.28, 95% CI 1.00 to 1.66, respectively).
|
21414601 |
2011 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate potential relations between rs2200733 versus clinical and electrocardiographic traits in a cohort of patients with early-onset AF who lack traditional risk factors.
|
21481830 |
2011 |
|
rs2200733
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The SNP rs2200733 on chromosome 4q25 is a risk factor for CE stroke related to AF only.
|
21574119 |
2011 |