Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042579
rs1042579
0.040 GeneticVariation BEFREE Thrombomodulin -33G/A and Ala455Val polymorphisms are associated with the risk of coronary artery disease: a meta-analysis including 12 584 patients. 25144670

2015

dbSNP: rs1042579
rs1042579
0.040 GeneticVariation BEFREE A combination of two common thrombomodulin gene variants (-1208-1209TTdelTT and A455V) influence risk of coronary heart disease: a prospective study in men. 15488871

2004

dbSNP: rs1042579
rs1042579
0.040 GeneticVariation BEFREE In smokers, the thrombomodulin Ala455Val variant allele emerges as a significant risk factor for coronary heart disease. 14523329

2003

dbSNP: rs1042620356
rs1042620356
0.010 GeneticVariation BEFREE Compound mutants for (MTHFD-G1958A, MTHFR-C677T and MTR-A2756G) and (MTHFD-G1958A, RFC1-G80A and MTR-A2756G) may increase the risk of CHD. 23701284

2013

dbSNP: rs1042713
rs1042713
0.020 GeneticVariation BEFREE Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease. 18473266

2008

dbSNP: rs1042713
rs1042713
0.020 GeneticVariation BEFREE Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease. 15797659

2005

dbSNP: rs1042714
rs1042714
0.030 GeneticVariation BEFREE Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease. 15797659

2005

dbSNP: rs1042714
rs1042714
0.030 GeneticVariation BEFREE Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease. 18473266

2008

dbSNP: rs1042714
rs1042714
0.030 GeneticVariation BEFREE To examine the role of the Gln27Glu polymorphism of β2-AR in HF development and to assess the hypothesis that Gln27Glu is associated with coronary artery disease in patients with ischaemic HF. 28933308

2018

dbSNP: rs10431335
rs10431335
0.700 GeneticVariation GWASDB A genome-wide association study of a coronary artery disease risk variant. 23364394

2013

dbSNP: rs1043618
rs1043618
0.010 GeneticVariation BEFREE By resequencing and genotyping, the associations of 2 single nucleotide polymorphisms (SNPs) +190G/C (rs1043618) and -110A/C (rs1008438) in the HSPA1A gene with risk of CHD were determined in a 1,003 pairs case-control study. 19333379

2009

dbSNP: rs1044250
rs1044250
0.010 GeneticVariation BEFREE Circulating Angptl4 levels may not influence TG levels or CHD risk for the following reasons: (1) Angptl4 levels were not correlated with TGs; (2) T266M, although associated with Angptl4 levels, showed no association with plasma TGs; and (3) TG-lowering E40K did not influence Angptl4 levels. 20829508

2010

dbSNP: rs1044925
rs1044925
0.010 GeneticVariation BEFREE Association between single nucleotide polymorphism rs1044925 and the risk of coronary artery disease and ischemic stroke. 24577316

2014

dbSNP: rs10455872
rs10455872
LPA
G 0.830 GeneticVariation GWASCAT Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib. 28753643

2017

dbSNP: rs10455872
rs10455872
LPA
0.830 GeneticVariation BEFREE For the best SNP rs10455872 for plasma Lp(a) levels, the OR for CHD, CVD, and CVD death was 0.94 (95% CI: 0.69-1.28), 0.97 (0.72-1.29), and 1.23 (0.79-1.92), respectively. 21900290

2012

dbSNP: rs10455872
rs10455872
LPA
0.830 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325

2014

dbSNP: rs10455872
rs10455872
LPA
0.830 GeneticVariation GWASDB Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 21966275

2011

dbSNP: rs10455872
rs10455872
LPA
0.830 GeneticVariation BEFREE In the replication cohort, rs10455872 was also associated with CHD events (odds ratio, 1.71; 95% confidence interval, 1.14-2.57; P=0.009). 29703846

2018

dbSNP: rs10455872
rs10455872
LPA
0.830 GeneticVariation BEFREE Extreme lipoprotein(a) levels or corresponding LPA KIV-2/rs10455872 risk genotypes substantially improved MI and CHD risk prediction. 23375930

2013

dbSNP: rs1045642
rs1045642
0.040 GeneticVariation BEFREE The association of MDR1 C3435T and G2677T/A polymorphisms with plasma platelet-activating factor levels and coronary artery disease risk in Turkish population. 23816407

2013

dbSNP: rs1045642
rs1045642
0.040 GeneticVariation BEFREE The C3435T polymorphism in the ABCB1 gene of fetus increases the risks of CHD in a Han Chinese population when the mothers are exposed to phthalates and alkylphenolic compounds during the periconceptional period, particularly for septal defects. 23874772

2013

dbSNP: rs1045642
rs1045642
0.040 GeneticVariation BEFREE The current meta-analysis suggests that ABCB1 C3435T polymorphism may contribute to the risk of CHD, especially for MI and ACS, among Caucasian populations. 24328528

2014

dbSNP: rs1045642
rs1045642
0.040 GeneticVariation BEFREE We sought to investigate maternal and child functional MDR1 C3435T polymorphism, periconception medication, folic acid use, and the risk of a congenital heart defect (CHD) in the offspring. 21183151

2011

dbSNP: rs10468017
rs10468017
0.700 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011

dbSNP: rs10484404
rs10484404
0.700 GeneticVariation GWASDB Genome-wide association study of coronary artery disease in the Japanese. 21971053

2012