|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The MTHFR C677T is not associated with an increased risk of vascular dementia or Alzheimer's disease.
|
10855603 |
2000 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To elucidate the specific role of the TT genotype of MTHFR in the development of cerebral infarction with and without cognitive impairment, we determined the prevalence of hyperhomocyst(e)inemia and the C677T genotypes of MTHFR in 143 patients with vascular dementia, 122 patients with cerebral infarction, and 217 healthy subjects matched for age and sex.
|
10938012 |
2000 |
|
rs7493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
(3-8) The importance of cardiovascular risk factors in the pathomechanism of Alzheimer's disease (AD) and vascular dementia (VD)(9-13) prompted us to examine the genetic effect of PON2 gene codon 311 (Cys-->Ser; PON2*S) polymorphism and the relationship between the PON2*S allele and the other dementia risk factor, the apoE polymorphism in these dementias.
|
11803456 |
2002 |
|
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The current results suggested that AGT T235M polymorphism might be a risk factor of vascular dementia.
|
16603315 |
2006 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The current results suggested that AGT T235M polymorphism might be a risk factor of vascular dementia.
|
16603315 |
2006 |
|
rs769665945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
While the ACE I/D, AT1R A1166C, and PAI-1 4G/5G did not contribute to the genetic susceptibility to vascular dementia (P>0.05), a significant association with vascular dementia was shown in the T235M polymorphism of AGT.
|
16603315 |
2006 |
|
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Pro10Leu of TGFB1 might be a risk factor of ischemic stroke and vascular dementia, especially for SVO in females.
|
16990569 |
2006 |
|
rs1799990
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Codon 129 (M129V) and 219 (Q219K) polymorphisms in Korean VaD patients were found in the open reading frame of PRNP.
|
17570906 |
2007 |
|
rs4925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Asp/Asp genotype of the Ala140Asp polymorphism of the GSTO1 gene has been alleged to increase the risk of vascular dementia.
|
17717316 |
2007 |
|
rs5882
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Neither the C-629A (P = 0.169) nor the I405V (P = 0.840) polymorphism was associated with VD risk in the whole sample.
|
19184337 |
2009 |
|
rs4986938
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The ESR2 rs4986938 polymorphism is associated with susceptibility for VaD in elderly Jewish women.
|
19473078 |
2009 |
|
rs1333049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, our data indicate for the first time that the C allele of rs1333049</span> in the vascular disease susceptibility locus is associated with VaD and LOAD, independent of traditional risk factors and the APOE ε4 genotype.
|
19664850 |
2011 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The MTHFR C677T polymorphism (mainly TT genotype) is associated with developing VaD in general populations or Asian populations.
|
20441995 |
2010 |
|
rs140701
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward.
|
20502016 |
2010 |
|
rs3813034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward.
|
20502016 |
2010 |
|
rs4795541
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward.
|
20502016 |
2010 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
While rs1800795 (CC or GC) genotypes alone increased the odds of developing VaD </span>by 2.2-fold, the presence of CC genotype of rs1801131 nullified this effect.
|
22015309 |
2012 |
|
rs1801131
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this case-control study, we examined C677T and A1298C (rs1801133 and rs1801131) polymorphism in the methylenetetrahydrofolate reductase (MTHFR) genes and their correlation with plasma levels of homocysteine (Hcy) in AD and VaD cases and evaluated the gene-gene interaction (epistasis) with IL-6-174 G/C (rs1800795).
|
22015309 |
2012 |
|
rs1801133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this case-control study, we examined C677T and A1298C (rs1801133 and rs1801131) polymorphism in the methylenetetrahydrofolate reductase (MTHFR) genes and their correlation with plasma levels of homocysteine (Hcy) in AD and VaD cases and evaluated the gene-gene interaction (epistasis) with IL-6-174 G/C (rs1800795).
|
22015309 |
2012 |
|
rs951660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor allele, A, of its intronic SNP 'rs951660' might induce a delayed splicing and thus increase the susceptibility to VaD.
|
22111664 |
2013 |
|
rs10491487
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of vascular dementia.
|
22116812 |
2012 |
|
rs12007229
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of vascular dementia.
|
22116812 |
2012 |
|
rs2497931
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of vascular dementia.
|
22116812 |
2012 |
|
rs26906
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of vascular dementia.
|
22116812 |
2012 |
|
rs4485213
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of vascular dementia.
|
22116812 |
2012 |