Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs290227
rs290227
SYK
G 0.810 GeneticVariation GWASDB We suggested a novel association of the VaD susceptibility with an intronic variant of rs290227 in the SYK gene. 23480133

2013
dbSNP: rs290227
rs290227
SYK
G 0.810 GeneticVariation GWASCAT We suggested a novel association of the VaD susceptibility with an intronic variant of rs290227 in the SYK gene. 23480133

2013
dbSNP: rs290227
rs290227
SYK
0.810 GeneticVariation BEFREE We suggested a novel association of the VaD susceptibility with an intronic variant of rs290227 in the SYK gene. 23480133

2013
dbSNP: rs117834366
rs117834366
CNTNAP2
A 0.700 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs429358
rs429358
APOE
C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs10491487
rs10491487
RASGRF2
0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs12007229
rs12007229 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs2497931
rs2497931 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs26906
rs26906
RASGRF2
0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs4485213
rs4485213 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE We identified APOE ɛ2/ɛ3/ɛ4 and additional four genetic polymorphisms including MTHFR C677T, PON1 L55M, TGF-β1 +29C/T, and TNF-α -850C/T associated with VaD. 25835425

2015
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE The MTHFR C677T polymorphism (mainly TT genotype) is associated with developing VaD in general populations or Asian populations. 20441995

2010
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE The MTHFR C677T is not associated with an increased risk of vascular dementia or Alzheimer's disease. 10855603

2000
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE To elucidate the specific role of the TT genotype of MTHFR in the development of cerebral infarction with and without cognitive impairment, we determined the prevalence of hyperhomocyst(e)inemia and the C677T genotypes of MTHFR in 143 patients with vascular dementia, 122 patients with cerebral infarction, and 217 healthy subjects matched for age and sex. 10938012

2000
dbSNP: rs5882
rs5882
CETP
0.020 GeneticVariation BEFREE CETP I405V polymorphism is likely a risk factor for AD and VaD in our cohort, independent of APOEɛ4 status. 29332048

2018
dbSNP: rs4986938
rs4986938
ESR2
0.020 GeneticVariation BEFREE In haplotype analyses, the ERβ haplotype containing the polymorphism rs944050 variant allele and the polymorphism rs4986938 wild-type allele was associated with VaD (odds ratio = 1.70, 95% confidence interval = 1.03-2.84). 22183267

2012
dbSNP: rs4986938
rs4986938
ESR2
0.020 GeneticVariation BEFREE The ESR2 rs4986938 polymorphism is associated with susceptibility for VaD in elderly Jewish women. 19473078

2009
dbSNP: rs5882
rs5882
CETP
0.020 GeneticVariation BEFREE Neither the C-629A (P = 0.169) nor the I405V (P = 0.840) polymorphism was associated with VD risk in the whole sample. 19184337

2009
dbSNP: rs17501010
rs17501010
CLDN1 ; LOC107986170
0.010 GeneticVariation BEFREE For patients with type 2 diabetes the odds ratio of VaD increased significantly in GC+CC genotypes of rs893051 (OR=12.57, P<0.0001) and GT+TT of rs17501010 (OR=5.33, P=0.01). 28273404

2017
dbSNP: rs893051
rs893051
CLDN1
0.010 GeneticVariation BEFREE For patients with type 2 diabetes the odds ratio of VaD increased significantly in GC+CC genotypes of rs893051 (OR=12.57, P<0.0001) and GT+TT of rs17501010 (OR=5.33, P=0.01). 28273404

2017
dbSNP: rs854560
rs854560
PON1
0.010 GeneticVariation BEFREE We identified APOE ɛ2/ɛ3/ɛ4 and additional four genetic polymorphisms including MTHFR C677T, PON1 L55M, TGF-β1 +29C/T, and TNF-α -850C/T associated with VaD. 25835425

2015
dbSNP: rs1051266
rs1051266
SLC19A1
0.010 GeneticVariation BEFREE No direct association was found between variant (G) allele or genotype of rs1051266 with AD and VaD cases. 24554143

2014
dbSNP: rs662
rs662
PON1
0.010 GeneticVariation BEFREE The interaction between PON1 genes (rs662 and rs85460) and ApoE genes showed synergistic epistasis in altering the odds of significantly having both AD and VaD. 24965284

2014
dbSNP: rs951660
rs951660
PHLDB2
0.010 GeneticVariation BEFREE The minor allele, A, of its intronic SNP 'rs951660' might induce a delayed splicing and thus increase the susceptibility to VaD. 22111664

2013
dbSNP: rs1800795
rs1800795
IL6 ; STEAP1B ; IL6-AS1
0.010 GeneticVariation BEFREE While rs1800795 (CC or GC) genotypes alone increased the odds of developing VaD </span>by 2.2-fold, the presence of CC genotype of rs1801131 nullified this effect. 22015309

2012