Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801131
rs1801131
0.010 GeneticVariation BEFREE In this case-control study, we examined C677T and A1298C (rs1801133 and rs1801131) polymorphism in the methylenetetrahydrofolate reductase (MTHFR) genes and their correlation with plasma levels of homocysteine (Hcy) in AD and VaD cases and evaluated the gene-gene interaction (epistasis) with IL-6-174 G/C (rs1800795). 22015309

2012

dbSNP: rs1801133
rs1801133
0.010 GeneticVariation BEFREE In this case-control study, we examined C677T and A1298C (rs1801133 and rs1801131) polymorphism in the methylenetetrahydrofolate reductase (MTHFR) genes and their correlation with plasma levels of homocysteine (Hcy) in AD and VaD cases and evaluated the gene-gene interaction (epistasis) with IL-6-174 G/C (rs1800795). 22015309

2012

dbSNP: rs944050
rs944050
0.010 GeneticVariation BEFREE The polymorphism rs944050 in the ERβ gene was associated with an increased risk of VaD in Chinese Han women. 22183267

2012

dbSNP: rs1333049
rs1333049
0.010 GeneticVariation BEFREE Altogether, our data indicate for the first time that the C allele of rs1333049</span> in the vascular disease susceptibility locus is associated with VaD and LOAD, independent of traditional risk factors and the APOE ε4 genotype. 19664850

2011

dbSNP: rs140701
rs140701
0.010 GeneticVariation BEFREE The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward. 20502016

2010

dbSNP: rs3813034
rs3813034
0.010 GeneticVariation BEFREE The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward. 20502016

2010

dbSNP: rs4795541
rs4795541
0.010 GeneticVariation BEFREE The analysis of the 3 markers rs3813034, rs140701 and rs4795541 spanning the SLC6A4 locus was made in 541 consecutive patients clinically diagnosed as having VaD (n = 372) or no cognitive impairment (n = 169) attending a geriatric ward. 20502016

2010

dbSNP: rs1799990
rs1799990
0.010 GeneticVariation BEFREE Codon 129 (M129V) and 219 (Q219K) polymorphisms in Korean VaD patients were found in the open reading frame of PRNP. 17570906

2007

dbSNP: rs4925
rs4925
0.010 GeneticVariation BEFREE The Asp/Asp genotype of the Ala140Asp polymorphism of the GSTO1 gene has been alleged to increase the risk of vascular dementia. 17717316

2007

dbSNP: rs1267969615
rs1267969615
ACE
0.010 GeneticVariation BEFREE The current results suggested that AGT T235M polymorphism might be a risk factor of vascular dementia. 16603315

2006

dbSNP: rs1800470
rs1800470
0.010 GeneticVariation BEFREE The Pro10Leu of TGFB1 might be a risk factor of ischemic stroke and vascular dementia, especially for SVO in females. 16990569

2006

dbSNP: rs699
rs699
AGT
0.010 GeneticVariation BEFREE The current results suggested that AGT T235M polymorphism might be a risk factor of vascular dementia. 16603315

2006

dbSNP: rs769665945
rs769665945
0.010 GeneticVariation BEFREE While the ACE I/D, AT1R A1166C, and PAI-1 4G/5G did not contribute to the genetic susceptibility to vascular dementia (P>0.05), a significant association with vascular dementia was shown in the T235M polymorphism of AGT. 16603315

2006

dbSNP: rs7493
rs7493
0.010 GeneticVariation BEFREE (3-8) The importance of cardiovascular risk factors in the pathomechanism of Alzheimer's disease (AD) and vascular dementia (VD)(9-13) prompted us to examine the genetic effect of PON2 gene codon 311 (Cys-->Ser; PON2*S) polymorphism and the relationship between the PON2*S allele and the other dementia risk factor, the apoE polymorphism in these dementias. 11803456

2002