Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs769665945
rs769665945
SERPINE1
0.010 GeneticVariation BEFREE While the ACE I/D, AT1R A1166C, and PAI-1 4G/5G did not contribute to the genetic susceptibility to vascular dementia (P>0.05), a significant association with vascular dementia was shown in the T235M polymorphism of AGT. 16603315

2006
dbSNP: rs854560
rs854560
PON1
0.010 GeneticVariation BEFREE We identified APOE ɛ2/ɛ3/ɛ4 and additional four genetic polymorphisms including MTHFR C677T, PON1 L55M, TGF-β1 +29C/T, and TNF-α -850C/T associated with VaD. 25835425

2015
dbSNP: rs893051
rs893051
CLDN1
0.010 GeneticVariation BEFREE For patients with type 2 diabetes the odds ratio of VaD increased significantly in GC+CC genotypes of rs893051 (OR=12.57, P<0.0001) and GT+TT of rs17501010 (OR=5.33, P=0.01). 28273404

2017
dbSNP: rs944050
rs944050
ESR2
0.010 GeneticVariation BEFREE The polymorphism rs944050 in the ERβ gene was associated with an increased risk of VaD in Chinese Han women. 22183267

2012
dbSNP: rs951660
rs951660
PHLDB2
0.010 GeneticVariation BEFREE The minor allele, A, of its intronic SNP 'rs951660' might induce a delayed splicing and thus increase the susceptibility to VaD. 22111664

2013
dbSNP: rs290227
rs290227
SYK
G 0.810 GeneticVariation GWASCAT We suggested a novel association of the VaD susceptibility with an intronic variant of rs290227 in the SYK gene. 23480133

2013
dbSNP: rs117834366
rs117834366
CNTNAP2
A 0.700 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs429358
rs429358
APOE
C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs290227
rs290227
SYK
G 0.810 GeneticVariation GWASDB We suggested a novel association of the VaD susceptibility with an intronic variant of rs290227 in the SYK gene. 23480133

2013
dbSNP: rs10491487
rs10491487
RASGRF2
0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs12007229
rs12007229 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs2497931
rs2497931 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs26906
rs26906
RASGRF2
0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012
dbSNP: rs4485213
rs4485213 		0.700 GeneticVariation GWASDB Genome-wide association study of vascular dementia. 22116812

2012