Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4820043
rs4820043
LIMK2
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs5749286
rs5749286
DRG1 ; SFI1
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs5749682
rs5749682
LARGE1
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs5750250
rs5750250
MYH9
G 0.700 GeneticVariation GWASCAT Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). 26305897

2015
dbSNP: rs6930576
rs6930576
SASH1
A 0.700 GeneticVariation GWASCAT A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs6997279
rs6997279
SLC30A8
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs7222331
rs7222331
KRTAP3-3
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs73206603
rs73206603
LOC107984625
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs735853
rs735853
MYH9
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs7916840
rs7916840
GPR158
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs9533481
rs9533481
ENOX1
0.700 GeneticVariation GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874

2011
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE This case-control study assessed the association of MTHFR C677T mutation in T2DM and DN cases. 21186995

2011
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE The methylenetetrahydrofolate reductase 677 C/T genotypes were determined in 174 type 2 diabetic patients: 80 with and 94 without renal failure due to diabetic nephropathy. 12784186

2003
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE Our study for the first time demonstrated a synergistic effect between ACE I/D with either MTHFR C677T or A1298C polymorphism on the increased risk of DN among patients with T2DM. 21942443

2012
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE Effects of the C677T and A1298C polymorphisms of the MTHFR gene on the genetic predisposition for diabetic nephropathy. 12897091

2003
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE Here, we first adopted methylenetetrahytrofolate reductase (MTHFR) gene C677T polymorphism as an instrument to infer the possible causal relevance between circulating homocysteine and DKD risk in a Chinese population and next attempted to build a risk prediction model for DKD. 30729677

2019
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE C677T polymorphism in MTHFR gene may be a risk factor for DN, but not for DM, in a Chinese population. 22209973

2012
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE The current meta-analysis suggested that MTHFR C677T polymorphism might influence DN risk, but not for DM in the Chinese population. 23822721

2013
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE Our findings suggest that the C677T mutation in the MTHFR gene predisposes type 2 diabetes patients to the development of diabetic nephropathy. 14737040

2004
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE The contribution of C677T single nucleotide polymorphism to increased risk of DN (presumably by increasing homocysteine concentrations) must be evaluated in the context of the ethnic background. 20524928

2010
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE The present study has investigated the role of endothelial nitric oxide (eNOS) G894T polymorphism and its interaction with methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C variants on the predisposition to diabetic nephropathy and its progression. 21380725

2011
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE In conclusion, although there is some evidence of association between MTHFR C677T gene polymorphism and DN, the above findings reinforce the need for further and more rigorous association studies. 17805475

2007
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes. 30397262

2019
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients. 16828193

2007
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE We observed a significant association of MTHFR C677T with development of diabetic nephropathy in type 2 diabetics. 23846111

2013