|
rs1229984
|
|
|
0.840 |
GeneticVariation |
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs1229984
|
|
|
0.840 |
GeneticVariation |
BEFREE |
In conclusion, our findings indicated that ADH1B (rs1229984) was associated with EC independent of alcohol drinking and tobacco smoking status and alcohol drinking interacted with ALDH2 (rs671) on EC susceptibility in this high-risk Chinese population.
|
22930414 |
2013 |
|
rs1229984
|
|
|
0.840 |
GeneticVariation |
BEFREE |
The functional polymorphisms ADH1B rs1229984 may contribute to susceptibility to esophageal cancer.
|
24093763 |
2014 |
|
rs1229984
|
|
|
0.840 |
GeneticVariation |
BEFREE |
ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis.
|
21048924 |
2010 |
|
rs3765524
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Results showed that the minor alleles of rs3765524, rs2274223, and rs10509670 were associated with increased risk of EC and GC.
|
30931333 |
2019 |
|
rs3765524
|
|
|
0.820 |
GeneticVariation |
GWASDB |
Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies.
|
22323360 |
2012 |
|
rs3765524
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Phospholipase C epsilon 1 (PLCE1 rs2274223A>G, rs3765524C>T and rs7922612C>T) polymorphisms and esophageal cancer risk in the Kashmir Valley.
|
24935391 |
2014 |
|
rs738722
|
|
|
0.810 |
GeneticVariation |
BEFREE |
The CT allele of SNP rs738722 and the GC allele of SNP rs2236142 might be a protective factor of the risk for lymph node metastasis of esophageal cancer.
|
22201027 |
2012 |
|
rs1042026
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs1042026
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs1042026
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs11066280
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs17450420
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs17450420
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs2074356
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs3805322
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs3805322
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs3805322
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs9288520
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs9288520
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.
|
22960999 |
2012 |
|
rs13042395
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Significant associations were found between SLC52A3 rs13042395 polymorphism and decreased cancer risk among esophageal cancer, Asians, female, normal BMI and old age groups.
|
27600099 |
2016 |
|
rs13042395
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Two SNPs, rs753955 and rs13042395, were associated with the risk of non-cardia GC in different genetic models (p < 0.05).No SNPs were associated with EC.
|
26176862 |
2015 |
|
rs13042395
|
|
|
0.730 |
GeneticVariation |
GWASDB |
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.
|
20729853 |
2010 |
|
rs13042395
|
|
|
0.730 |
GeneticVariation |
BEFREE |
However, there was no significant association between the C20orf54 rs13042395 genotype and esophageal cancer risk (adjusted OR = 0.99, 95 % CI = 0.63-1.57 for C20orf54 rs13042395 TT vs. CC).
|
22744421 |
2012 |
|
rs10931936
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Four of the 20 SNPs identified as high-risk SNPs in Chinese esophageal cancer showed increased risk for Chinese lung cancer, which included rs3769823 (OR = 1.26; 95% CI = 1.107-1.509; P = 0.02), rs10931936 (OR = 1.283; 95% CI = 1.100-1.495; P = 0.04), rs2244438 (OR = 1.294; 95% CI = 1.098-1.525; P = 0.04) and rs13016963 (OR = 1.268; 95% CI = 1.089-1.447; P = 0.04).
|
28542283 |
2017 |