|
rs1800566
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association between NQO1 Pro187Ser polymorphism and esophageal cancer: a meta-analysis.
|
24213850 |
2014 |
|
rs1258159645
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between NQO1 Pro187Ser polymorphism and esophageal cancer: a meta-analysis.
|
24213850 |
2014 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis.
|
26345834 |
2015 |
|
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis.
|
26345834 |
2015 |
|
rs878854066
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis.
|
26345834 |
2015 |
|
rs6869366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the XRCC4 rs6869366 G allele (GT+GG) were at a significantly higher risk of esophageal cancer compared to individuals with the TT genotype [odds ratio (OR)=3.35, 95% confidence interval (CI): (1.16-10.24)].
|
25612937 |
2015 |
|
rs1035142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Caspase8 rs1035142 G>T polymorphism was associated with an increased risk of esophageal cancer in a Chinese population.
|
24464182 |
2014 |
|
rs4938723
|
|
|
0.020 |
GeneticVariation |
BEFREE |
CONCLUSIONS Current meta-analysis suggested that rs4938723 polymorphism was potentially associated with hepatocellular carcinoma risk, but this polymorphism had a decreased association for susceptibility to esophageal cancer, leukemia, and colorectal cancer.
|
30286050 |
2018 |
|
rs1801131
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cox regression revealed ypT category (P = 0.001) and lymphatic vessel invasion (P = 0.03) to be independent prognostic factors for esophageal cancer, and histopathological response (P = 0.01), MTHFR variant (rs1801131, P = 0.002), and ypN category (P = 0.02) to be prognostic factors for gastric cancer.
|
21347786 |
2011 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Crude odds ratios (ORs) with 95% confidence intervals (CIs) were assessed for EC risk associated with TP53 Arg72Pro polymorphism using fixed- and random-effects models.
|
21448430 |
2011 |
|
rs1131691014
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Crude odds ratios (ORs) with 95% confidence intervals (CIs) were assessed for EC risk associated with TP53 Arg72Pro polymorphism using fixed- and random-effects models.
|
21448430 |
2011 |
|
rs878854066
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Crude odds ratios (ORs) with 95% confidence intervals (CIs) were assessed for EC risk associated with TP53 Arg72Pro polymorphism using fixed- and random-effects models.
|
21448430 |
2011 |
|
rs758272654
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Determination of T393C-SNP preoperatively will allow allocation of EC patients into different risk profiles which may help to stratify patients eligible for neoadjuvant and or adjuvant therapy.
|
21340746 |
2011 |
|
rs181206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Disease type-stratified subgroup analysis yielded increased risk of related diseases in IL-27 rs181206 T>C carriers in the allele model in immune thrombocytopenia (ITP), asthma, and esophageal cancer (EC) subgroups (ITP: OR=0.69, 95%CI=0.53~0.88, P=0.004; asthma: OR=0.60, 95%CI=0.41~0.89, P=0.010; EC: OR=0.79, 95%CI=0.64~0.97, P=0.026); and IL-27 rs153109 A>G polymorphism was remarkably associated with the increased risk of related diseases in the allele model in ovarian cancer (OC), systemic lupus erythematosus (SLE), tuberculosis (TB), ulcerative colitis (UC), and chronic obstructive pulmonary disease (COPD) subgroups (all P<0.05).
|
26950245 |
2016 |
|
rs153109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Disease type-stratified subgroup analysis yielded increased risk of related diseases in IL-27 rs181206 T>C carriers in the allele model in immune thrombocytopenia (ITP), asthma, and esophageal cancer (EC) subgroups (ITP: OR=0.69, 95%CI=0.53~0.88, P=0.004; asthma: OR=0.60, 95%CI=0.41~0.89, P=0.010; EC: OR=0.79, 95%CI=0.64~0.97, P=0.026); and IL-27 rs153109 A>G polymorphism was remarkably associated with the increased risk of related diseases in the allele model in ovarian cancer (OC), systemic lupus erythematosus (SLE), tuberculosis (TB), ulcerative colitis (UC), and chronic obstructive pulmonary disease (COPD) subgroups (all P<0.05).
|
26950245 |
2016 |
|
rs353163
|
|
|
0.020 |
GeneticVariation |
BEFREE |
ECRG1 Arg290Gln polymorphism significantly conferred 1.8-fold increased risk of EC in dominant model (odds ratio = 1.78, 95% confidence interval = 1.27-2.49, P = 0.001).
|
23869757 |
2013 |
|
rs465498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms (SNPs), rs465498, rs17728461, rs4488809, rs753955, rs13361707, rs9841504, rs2274223, and rs13042395, were reported by genome wide association studies (GWASs) to be closely related to the susceptibility of lung cancer (LC), gastric cancer (GC) or esophageal cancer (EC) in Han population from northern or southern China.
|
26176862 |
2015 |
|
rs17728461
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms (SNPs), rs465498, rs17728461, rs4488809, rs753955, rs13361707, rs9841504, rs2274223, and rs13042395, were reported by genome wide association studies (GWASs) to be closely related to the susceptibility of lung cancer (LC), gastric cancer (GC) or esophageal cancer (EC) in Han population from northern or southern China.
|
26176862 |
2015 |
|
rs2274223
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms (SNPs), rs465498, rs17728461, rs4488809, rs753955, rs13361707, rs9841504, rs2274223, and rs13042395, were reported by genome wide association studies (GWASs) to be closely related to the susceptibility of lung cancer (LC), gastric cancer (GC) or esophageal cancer (EC) in Han population from northern or southern China.
|
26176862 |
2015 |
|
rs2234922
|
|
|
0.060 |
GeneticVariation |
BEFREE |
EPHX1 exon 4 139His/Arg, and 139Arg/Arg genotypes were associated with a higher risk of esophageal cancer in a high-risk area of India.
|
20659238 |
2010 |
|
rs583522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of the germline single nucleotide polymorphism rs583522 in the TNFAIP3 gene as a prognostic marker in esophageal cancer.
|
26598072 |
2015 |
|
rs174538
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Flap endonuclease-1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population.
|
28319330 |
2017 |
|
rs1364898025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four distinct sequence alterations were identified: (a) in one gastric and one esophageal tumor, an A to C transversion occurred at nucleotide 5795 (CAC-->CCC), leading to a His-->Pro substitution at codon 179; (b) a second esophageal tumor had a C to T transition at nucleotide 8291 (ACC-->ATC), leading to a Thr-->Ile substitution at codon 277 of IGFBP-3; (c) one alteration comprised a G to C transversion in exon 1 at nucleotide 2132 (GGG-->GCG), leading to a Gly-->Ala substitution at codon 32 in two gastric cancers, seven esophageal cancers, and nine colon cancers; and (d) a C to G transversion located 17 nucleotides from the 3' splice site in intron 1 was observed in three colon cancers and four esophageal cancers.
|
9809981 |
1998 |
|
rs2854746
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four distinct sequence alterations were identified: (a) in one gastric and one esophageal tumor, an A to C transversion occurred at nucleotide 5795 (CAC-->CCC), leading to a His-->Pro substitution at codon 179; (b) a second esophageal tumor had a C to T transition at nucleotide 8291 (ACC-->ATC), leading to a Thr-->Ile substitution at codon 277 of IGFBP-3; (c) one alteration comprised a G to C transversion in exon 1 at nucleotide 2132 (GGG-->GCG), leading to a Gly-->Ala substitution at codon 32 in two gastric cancers, seven esophageal cancers, and nine colon cancers; and (d) a C to G transversion located 17 nucleotides from the 3' splice site in intron 1 was observed in three colon cancers and four esophageal cancers.
|
9809981 |
1998 |
|
rs748676559
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four distinct sequence alterations were identified: (a) in one gastric and one esophageal tumor, an A to C transversion occurred at nucleotide 5795 (CAC-->CCC), leading to a His-->Pro substitution at codon 179; (b) a second esophageal tumor had a C to T transition at nucleotide 8291 (ACC-->ATC), leading to a Thr-->Ile substitution at codon 277 of IGFBP-3; (c) one alteration comprised a G to C transversion in exon 1 at nucleotide 2132 (GGG-->GCG), leading to a Gly-->Ala substitution at codon 32 in two gastric cancers, seven esophageal cancers, and nine colon cancers; and (d) a C to G transversion located 17 nucleotides from the 3' splice site in intron 1 was observed in three colon cancers and four esophageal cancers.
|
9809981 |
1998 |