|
rs1582417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study provided the first evidence for the impact of rs1582417, rs17057846, rs2431689, rs2961920, rs58747524, and rs7727115 polymorphisms in MIR3142HG on the susceptibility to and/or prognosis of glioma in the Chinese Han population.
|
31513017 |
2020 |
|
rs17057846
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the risk analysis, rs17057846 (odds ratio [OR]=1.93, P=0.047), rs2961920 (OR=1.53, P=0.019), and rs58747524 (OR=1.23, P=0.046) polymorphisms were associated with increased glioma risk, while rs7727115 (OR=0.76, P=0.030) and rs1582417 (female individuals, OR=0.49, P=0.017) variants were associated with decreased risk.
|
31513017 |
2020 |
|
rs2961920
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the risk analysis, rs17057846 (odds ratio [OR]=1.93, P=0.047), rs2961920 (OR=1.53, P=0.019), and rs58747524 (OR=1.23, P=0.046) polymorphisms were associated with increased glioma risk, while rs7727115 (OR=0.76, P=0.030) and rs1582417 (female individuals, OR=0.49, P=0.017) variants were associated with decreased risk.
|
31513017 |
2020 |
|
rs58747524
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study provided the first evidence for the impact of rs1582417, rs17057846, rs2431689, rs2961920, rs58747524, and rs7727115 polymorphisms in MIR3142HG on the susceptibility to and/or prognosis of glioma in the Chinese Han population.
|
31513017 |
2020 |
|
rs7727115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study provided the first evidence for the impact of rs1582417, rs17057846, rs2431689, rs2961920, rs58747524, and rs7727115 polymorphisms in MIR3142HG on the susceptibility to and/or prognosis of glioma in the Chinese Han population.
|
31513017 |
2020 |
|
rs1044129
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study evaluated the role of TYMS (rs1059394, C > T, and rs2847153, G > A), RYR3 (rs1044129, G > A), KIAA0423 (rs1053667, T > C), and GOLGA7 (rs11337, G > T) polymorphisms for assessment of glioma risk and prognosis among the Chinese Han population.
|
31525662 |
2019 |
|
rs1053667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study evaluated the role of TYMS (rs1059394, C > T, and rs2847153, G > A), RYR3 (rs1044129, G > A), KIAA0423 (rs1053667, T > C), and GOLGA7 (rs11337, G > T) polymorphisms for assessment of glioma risk and prognosis among the Chinese Han population.
|
31525662 |
2019 |
|
rs1057519902
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
|
rs1131239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that haplotype ″GACCG″ in the block (rs41278075, rs2306420, rs117677079, rs2306415 and rs1131239) significantly decreased the susceptibility of glioma (OR 0.61, p = 0.003).
|
30536196 |
2019 |
|
rs11337
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that GOLGA7 (rs11337) polymorphism may play a role in the prognosis of glioma patients and that TYMS (rs1059394) is associated with glioma risk.
|
31525662 |
2019 |
|
rs117677079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that haplotype ″GACCG″ in the block (rs41278075, rs2306420, rs117677079</span>, rs2306415 and rs1131239) significantly decreased the susceptibility of glioma (OR 0.61, p = 0.003).
|
30536196 |
2019 |
|
rs1339499
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, cumulative associations of rs473426 and rs1339499 with glioma risk were observed (P = 0.011).
|
31773361 |
2019 |
|
rs145619195
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Whereas, rs145619195 CT genotype might weaken the susceptibility (OR 0.63, p = 0.024) and prognosis (HR 0.20, p = 0.025) of glioma.
|
30536196 |
2019 |
|
rs145929329
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three adult glioma risk variants, rs634537, rs2157719, and rs145929329, all mapping to the 9p21.3 (<i>CDKN2B-AS1</i>) locus, were associated with glioma risk in children and AYA.
|
31040135 |
2019 |
|
rs1553260624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
|
rs2235544
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C-allele of the DI01 SNP rs2235544 was related to increased circulating free T3/ free T4 ratio in glioma and meningioma patients, indicating greater T4 to T3 conversion.
|
31452060 |
2019 |
|
rs2239647
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratified analysis showed that rs2239647 increased the risk of glioma in female (OR = 1.62, p = 0.016).
|
31759389 |
2019 |
|
rs2279115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analyses by sex elucidated that BCL-2 rs2279115</span> was significantly associated with glioma</span> risk in males (OR = 0.41, 95% CI = 0.30-0.58, p = 1.0 × 10<sup>-7</sup>), but not in females (p > 0.05).
|
30481055 |
2019 |
|
rs2306415
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that haplotype ″GACCG″ in the block (rs41278075, rs2306420, rs117677079, rs2306415 and rs1131239) significantly decreased the susceptibility of glioma (OR 0.61, p = 0.003).
|
30536196 |
2019 |
|
rs2306420
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that haplotype ″GACCG″ in the block (rs41278075, rs2306420, rs117677079, rs2306415 and rs1131239) significantly decreased the susceptibility of glioma (OR 0.61, p = 0.003).
|
30536196 |
2019 |
|
rs3213801
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, our results indicated that POLK variants rs3213801 and rs5744533 are not associated with glioma risk and prognosis.
|
31595696 |
2019 |
|
rs34988193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IMPLICATIONS: This is the first study presenting an approach to screening many germline variants to identify variants predictive of survival and our application of this methodology revealed the germline variants rs61757955 and rs34988193 as being predictive of survival in patients with lower grade glioma.
|
30651372 |
2019 |
|
rs3787016
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Impact of four lncRNA polymorphisms (rs2151280, rs7763881, rs1136410, and rs3787016) on glioma risk and prognosis: A case-control study.
|
31489712 |
2019 |
|
rs41278075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that haplotype ″GACCG″ in the block (rs41278075, rs2306420, rs117677079, rs2306415 and rs1131239) significantly decreased the susceptibility of glioma (OR 0.61, p = 0.003).
|
30536196 |
2019 |
|
rs4598633
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Rs7115578 polymorphism had a lower susceptibility to glioma in males (OR = 0.68, P=0.034), while rs4598633 variant with a higher risk in females (OR = 1.66, P=0.016).
|
31652449 |
2019 |