rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Gene polymorphisms of adducin GLY460TRP, ACE I/D, AND AGT M235T in pediatric hypertension patients.
|
25262176 |
2014 |
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The ThrThr genotype of the angiotensinogen (AGT) Met235Thr polymorphism has been associated with elevated AGT levels, hypertension, increased heart disease risk, and improved blood pressure (BP) response to angiotensin-converting enzyme (ACE) inhibitors.
|
14643574 |
2003 |
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There are inconsistent reports that the angiotensinogen (ATG) variant Met235-->Thr (T235) allele and angiotensin-converting enzyme (ACE) insertion/deletion (I/D) variants are associated with hypertension and related target organ damage.
|
10487325 |
1999 |
rs1415088003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of the study was to verify the hypothesis if the interaction between the G protein beta3 subunit (GNB3) C825T polymorphism and ACE I/D polymorphism could lead to the disclosure of increased activity of sodium-proton exchanger and hypertension.
|
16314202 |
2006 |
rs1415088003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Synergistic Effects of ACE Insertion/Deletion and GNB3 C825T Polymorphisms on the Efficacy of PDE-5 Inhibitor in Patients with Pulmonary Hypertension.
|
26821322 |
2016 |
rs4305
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A polymorphism in ACE (rs4305) showed modest replication of association with increased hypertension (β: 0.06 mm Hg; SE: 0.01 mm Hg; meta-analysis: P=3.0×10(-5)).
|
21444836 |
2011 |
rs4305
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The MDR analysis demonstrated that the interaction between BMI and rs4305 increased the susceptibility to hypertension.
|
24015270 |
2013 |
rs568401628
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In adolescents of European origin, hypertension is associated with an increased degree of obesity among other characteristics of the metabolic syndrome; the Trp64Arg variant of the beta3-adrenergic receptor gene may favor the central adiposity gain.
|
14739355 |
2004 |
rs568401628
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results are consistent with the thesis that the Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated more often with the condition of high blood pressure than with normal blood pressure.
|
10100091 |
1999 |
rs1042309696
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
|
18212314 |
2008 |
rs1156835126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
rs142677199
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the A640G gene variation with the presence and extent of CAD was not only identified in the total sample, but was even stronger in various high risk subpopulations of younger individuals (e.g. with hypertension with or without increased apolipoprotein B plasma levels).
|
10488959 |
1999 |
rs1799752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not observe associations between hypertension and rs1799752 (<i>P</i>=0.422), rs699 (<i>P</i>=0.36), rs5186 (<i>P</i>=0.49), and rs1799998 (<i>P</i>=0.71).
|
31511791 |
2019 |
rs4291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571).
|
21157371 |
2011 |
rs4362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When the cohort was stratified by sex, ACE rs4362 and AGT rs699 showed significant associations with WMLs in men only (P = 0.01 and P = 0.03, respectively), and remained significant after controlling for hypertension.
|
24622918 |
2014 |
rs4363
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Under a dominant model, rs4291 rs4335, rs4344, rs4353, rs4362, and rs4363 polymorphisms were associated with an increased risk of hypertension after adjusting for age, gender, BMI, triglycerides, alcohol consumption, and smoking.
|
23741507 |
2013 |
rs553520266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
rs746566272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
rs755506668
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
rs761401927
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the A640G gene variation with the presence and extent of CAD was not only identified in the total sample, but was even stronger in various high risk subpopulations of younger individuals (e.g. with hypertension with or without increased apolipoprotein B plasma levels).
|
10488959 |
1999 |