|
rs62571442
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs rs12402181 in miR-3117 and rs62571442 in miR-3689d2 were associated with ALL risk in both cohorts, possibly through their effect on MAPK signalling pathway.
|
29796161 |
2018 |
|
rs861530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>XRCC3</i> rs1799794, rs45603942, rs1799796, and rs861530 were not significantly associated with the risk of childhood ALL in the Taiwanese population.
|
30532590 |
2018 |
|
rs861539
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that <i>XRCC3</i> genotypes with polymorphisms at rs861539 may play a role in determining individual susceptibility to childhood ALL in this Taiwanese population.
|
30532590 |
2018 |
|
rs885822
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variation in rs885822 was found to be associated with overall survival: patients carrying the GG genotype demonstrated a significantly increased risk of death compared to those carrying the A allele, independently of ALL risk groups (HR 3.13, 95%CI 1.16-7.8, p = 0.014).
|
29304394 |
2018 |
|
rs10235796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The IKZF1 SNPs, rs10235796 and rs6964969, and the CDKN2A SNP rs3731246 (previously unreported) could serve as risk markers for ALL susceptibility in Yemeni children.
|
28768142 |
2017 |
|
rs116855232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recently, few studies reported on an inherited nucleoside diphosphate-linked moiety X motif 15 (NUDT15) c.415C>T low-function variant that is associated with decreased thiopurine metabolism and leukopenia in childhood acute lymphoblastic leukemia (ALL) and other diseases.
|
27577869 |
2017 |
|
rs12434881
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to evaluate the contribution of IL10 A-1082G (rs1800896), T-819C (rs3021097) and A-592C (rs1800872) genotypes to the risk of childhood acute lymphoblastic leukemia (ALL) in Taiwan.
|
27107085 |
2017 |
|
rs1800896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to evaluate the contribution of IL10 A-1082G (rs1800896), T-819C (rs3021097) and A-592C (rs1800872) genotypes to the risk of childhood acute lymphoblastic leukemia (ALL) in Taiwan.
|
27107085 |
2017 |
|
rs199737785
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined the possible relationship between three RAGE polymorphisms, -429C/T, -374 T/A, and 63-bp deletion, and susceptibility to childhood acute lymphoblastic leukemia (ALL) in an Iranian population.
|
28045617 |
2017 |
|
rs2114358
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results replicate the association between rs2114358 in miR-1206 and MTX-induced oral mucositis in childhood ALL.
|
28628559 |
2017 |
|
rs2274407
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ABCC4 G912T SNP was genotyped in 145 Iranian Philadelphia-negative (Ph<sup>-</sup>) children with ALL using modified tetra-primer ARMS PCR and evaluated for possible association with 3-year disease-free survival (3DFS).
|
28550450 |
2017 |
|
rs2811709
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs2811712, rs3731249, rs3217992 and rs2811709 were associated with B-ALL susceptibility in our Spanish population.
|
28481918 |
2017 |
|
rs3021097
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to evaluate the contribution of IL10 A-1082G (rs1800896), T-819C (rs3021097) and A-592C (rs1800872) genotypes to the risk of childhood acute lymphoblastic leukemia (ALL) in Taiwan.
|
27107085 |
2017 |
|
rs3217992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs2811712, rs3731249, rs3217992 and rs2811709 were associated with B-ALL susceptibility in our Spanish population.
|
28481918 |
2017 |
|
rs35134728
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping for MTHFR rs3737966 and rs35134728 in 144 children with ALL was performed using the Sequenom MassArray system (Sequenom, San Diego, CA, USA).
|
28990296 |
2017 |
|
rs35837782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After genotyping an additional 2525 cases and 3575 controls, we identify new susceptibility loci for BCP-ALL mapping to 10q26.13 (rs35837782, LHPP, P=1.38 × 10<sup>-11</sup>) and 12q23.1 (rs4762284, ELK3, P=8.41 × 10<sup>-9</sup>).
|
27694927 |
2017 |
|
rs3731246
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The IKZF1 SNPs, rs10235796 and rs6964969, and the CDKN2A SNP rs3731246 (previously unreported) could serve as risk markers for ALL susceptibility in Yemeni children.
|
28768142 |
2017 |
|
rs3733890
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BHMT (rs3733890) polymorphism showed no association with ALL.
|
28582843 |
2017 |
|
rs3737966
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping for MTHFR rs3737966 and rs35134728 in 144 children with ALL was performed using the Sequenom MassArray system (Sequenom, San Diego, CA, USA).
|
28990296 |
2017 |
|
rs3794012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs4237770
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs442264
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we sought to determine a potential association between the variant rs4880 in SOD2 gene, a key mitochondrial enzyme that protects cells against ROS, and hepatotoxicity during asparaginase-based therapy in 224 patients enrolled on CALGB-10102, a treatment trial for adults with ALL.
|
27019981 |
2017 |
|
rs62527607
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results showed a robust association between the rs62527607 SNP and the risk of relapse in ALL, but not AML, patients.
|
27372260 |
2017 |